Browse our Research Articles

Peptides designed by artificial intelligence restrict both drug-resistant bacteria and rapidly evolving viruses.

Prevention of either lipid uptake or lipid catabolism in infected macrophages restricts the ability of Mycobacterium tuberculosis to grow inside these cells.

Using single-cell RNA sequencing, we mapped thousands of expression quantitative trait loci in yeast, including a variant in GPA1 that influences gene expression, cell-cycle occupancy, and mating efficiency.

Congenital deafness increases individual differences in brain connectivity from the auditory cortex, particularly to language-related regions, highlighting how sensory loss shapes brain organization and development and the importance of personalized rehabilitation.

Identification and characterization of enhancers for eight key arterial genes reveal transcription factors associated with different aspects of endothelial gene expression specificity and provide a tool for a better understanding of arterial differentiation.

Genome-wide CRISPR screen identified propionyl-CoA subunit B as a key regulator for anti-tumor T-cell activity in pancreatic cancer, which holds promise for advancing immunotherapy strategies in curing pancreatic cancer.

A fly’s preference for one odor versus another can be predicted by the idiosyncratic activity of neurons early on in the olfactory information processing circuit.

DLK signaling network reveals the conserved function in neuritogenesis and synapse formation, and highlights the regulation of c-Jun translation and microtubule homeostasis in hippocampal selective neuron vulnerability.

Derived from scRNA-seq, SLC26A3 is a potential therapeutic target to improve the efficacy of immunotherapy, as well as a potential diagnostic indicator to reduce post-surgical upstaging, for cervical adenocarcinoma.

Single-cell multiomic analyses reveal known and new genes and pathways involved in the development of germ cells and provide a discovery platform for the scientific community.