Magnetic resonance imaging, through its sensitivity to ionic environments that modulate membrane potential, enables noninvasive assessment of biological systems.
CCR4 expression in Tregs is critical for limiting proinflammatory Th1 cell-mediated immune responses and atherosclerosis by maintaining the suppressive and migratory functions of Tregs.
Mechanistic modeling with low-rank recurrent networks uncovers the relationship between network connectivity, neural dynamics, and selection modulation mechanisms in context-dependent computation.
Maximilian Nentwich, Marcin Leszczynski ... Lucas C Parra
A new computational model improves estimation of Granger connectivity by removing spurious effects of external inputs, and estimation of linear encoding models by removing spurious effects of recurrent connections.
Extended multi-attribute attentional drift diffusion model reveals how attentional dynamics and weight shifts lead to less healthy decisions under hunger.
The jellyfish embryonic body axis is globally coordinated by conserved planar cell polarity (PCP) mechanisms and oriented by localised Wnt3 in two steps, highlighting PCP’s role in animal axis evolution.
Cryo-electron microscopy and high-speed atomic force microscopy analyses of an epilepsy-related ligand–receptor complex LGI1–ADAM22 reveal the three-dimensional structure and dynamics of the 3:3 heterohexameric assembly of LGI1–ADAM22.
Although eIF2A is thought to be a translation initiation factor, loss of eIF2A has no effect on cellular mRNA translation in either unstressed or stressed conditions.
SHAPE-MaP reveals functional RNA structures in the porcine epidemic diarrhea virus genome, enabling targeted siRNA design and offering a promising strategy to inhibit viral replication.
