Browse our Research Articles

Acetylation of nuclear basket components, following their interaction with accumulating extrachromosomal DNA circles, drives the reorganization of nuclear pore complexes and the loss of cellular viability associated with replicative ageing.

Olfactory neurons of insects, once thought to express only a single type of olfactory receptor, exhibit widespread co-expression of receptors from multiple chemosensory gene families.

Tailoring Boolean models to 488 prostate cancer patients and 8 cell lines data allows for the experimentally validated personalisation of drug treatments.

A simple mechanism relying on microtubule rescues occurring at midzone edges allows fission yeast spindles to elongate during anaphase B while maintaining microtubule overlaps, without the need to precisely regulate microtubule growth speed.

Physiological evidence shows that the pupillary response to imagined light can be used to index the strength and vividness of an individual’s visual imagery and as a new tool for confirming aphantasia.

The interplay of the host metabolic reprogramming, its negative association with antiviral biological signaling pathways and the IFN-mediated host antiviral mechanism during Crimean–Congo hemorrhagic fever orthonairovirus (CCHFV) infection could provide attractive options for therapeutic intervention of CCHF.

The MCM-binding protein (MCMBP) promotes the hexamer assembly of the replicative MCM2–7 helicase by interacting with the nascent MCM3 subunit, playing a key role in achieving high expression levels of the functional MCM2–7 helicase for maintaining genome integrity.

Human sensorimotor learning is associated with changes in the structure of cognitive and motor functional brain networks, and reconfiguration processes occurring in these networks are associated with distinct patterns of subject learning and relearning.

The first demonstration that cellular ATP homeostasis suppresses high volatility of cellular ATP levels to ensure proteostasis that prevents accumulation of cytotoxic protein aggregation.

Tissue-level cell tracking and analysis of actomyosin and N-cadherin adhesion dynamics, coupled with disruption of the regulatory gene Shroom3, reveals region-specific cell behaviors along the anteroposterior axis during neural tube closure.