Browse our Research Articles

A comprehensive analysis of mutant animal model shows the important role of KDM6B and how it cooperates with TFDP1 to achieve its functional specificity in regulating Trp53 expression to control the fate of cranial neural crest cells during palatogenesis.

Proline is essential for osteoblast differentiation and bone formation by facilitating the production of proline-enriched osteoblast proteins.

Intercellular communication is critical for organ function, and the role of innervation in mediating this communication is of relevance to many fields, including developmental biology, neuroendocrinology, and disease pathophysiology.

A mathematical model of colorectal cancer initiation shows that a change in cells’ kinetic parameters due to aspirin can account for an observed reduction in advanced adenoma age- incidence in patients treated with aspirin.

Experimentally validated structural models of ACKR1-LukE and CCR5-LukE complexes reveal the critical contributions of sulfotyrosine binding sites and divergent loops of Staphylococcus aureus leukotoxins to the recognition of chemokine receptors.

Computed decisions degrade in working memory in a manner that depends on one of two strategies used to store relevant information as revealed by mathematical analysis of behavioral response patterns.

Wings achieve plasticity in size while maintaining robust pattern via ecdysone, which elicits graded responses for growth rates and threshold responses for patterning rates, in the fruit fly Drosophila melanogaster.

Muscle hypertrophy and regeneration are critically regulated by combination of TGF-β type I receptors in myofibres.

Chronic, daily inhalation of e-cigarette aerosols alters the inflammatory state of multiple organ systems, including the brain, heart, lung and colon.

An improved conditional gene-based association analysis framework guided by multiple variant-gene mapping strategies was built and evaluated based on its performance in predicting the potential susceptibility isoforms, genes, and tissues of schizophrenia.