Browse our Research Articles

Experiments in a mouse model for Alzheimer’s disease using germ-free and conventionally housed animals reveal that microbiota-derived short-chain fatty acids promote the deposition of cerebral Aβ plaques.

Cell competition is an important mechanism selecting against aneuploid cells.

A novel reporter model system serves as a valuable tool for studying latent HIV-1 infection and identifies potent latency reversing agent.

Molecular mechanisms reveal that human cytomegalovirus has evolved to deploy two individual glycoproteins working in synergy to efficiently evade antibody-mediated immunity mediated by Fc-gamma receptors.

Throughout learning, both unexpected outcomes and the predictive value of cues modulate learning rate and episodic memory, thereby supporting two seemingly opposing theories of associative learning.

Extended somatic hypermutation and clonal evolution associated with antibody neutralization breath in HIV controllers with low plasma viral loads provide promise for HIV vaccine development.

Heterotrimeric G-proteins can be switched on not only by G-protein-coupled receptors but also by cytoplasmic proteins, resulting in different signaling mechanisms in cells depending on the specific type of activator.

Rab25a and Rab25b mutant embryos exhibit epithelial spreading delays during morphogenesis and are characterized by cytokinesis defects leading to cell fusions, heterogeneous epithelial cell sizes, and reduced cortical actomyosin contractility.

Early suPAR-guided anakinra decreases the risk for severe respiratory failure in SARS-CoV-2 pneumonia and restores the pro-/anti-inflammatory balance.

Mechanical loading and the bone anabolic action of parathyroid hormone result in rapid, lysosomal degradation of sclerostin protein, revealing physiologically important post-translational control of this critical regulator of bone formation.