Browse our Research Articles

The histone demethylase KDM5 functions in concert with the transcription factor Prospero to regulate a gene expression program that is required for mushroom body neuroanatomical development.

Problematic design features in the stop-signal task for the massive Adolescent Brain Cognitive Development (ABCD) study undermine analyses of the shared data, but can be mitigated with proposed solutions.

Structures of the GluK2/K5 kainate receptor reveal the heteromer architecture and how the receptor organizes in apo, antagonist-bound, and desensitized states.

A single-stranded DNA binding protein stimulates helicase-mediated DNA unwinding by transiently activating a latent processivity switch in the helicase.

SARS-CoV-2 can spread efficiently within care homes causing outbreaks among residents, who are at increased risk of severe disease, emphasising the importance of stringent infection control in this population.

Epigenetic determination of tissue of origin of genetically classified subsets of plasma DNA molecules enhances transplantation monitoring and cancer testing.

Temporal changes in genome-wide enhancer transcription activity during a transdifferentiation event reveal additive and synergistic enhancer cooperation.

Wnt signaling is revealed to be a regulator of macrophage inflammation-resolving state in atherosclerosis through a PGE2-mediated pathway.

A circuit involving Tacr1-expressing neurons in the spinal cord and the parabrachial nucleus controls how mice respond to a wide range of persistently painful stimuli.

Individual differences in intelligence are based on information processing that is embedded in fine-scale structure in cortical systems for self-generated thought, which was revealed by resolving topographic idiosyncrasies with hyperalignment.