Marcks and Marcks-like 1 proteins are required for normal neurite formation and proliferation of neuro-glial progenitors during development and regeneration of the Xenopus spinal cord implicating these proteins as critical new factors for spinal cord development and regeneration.
Xuankun Li, Adriana E Marvaldi ... Duane D McKenna
The evolutionary trajectory of phytophagous weevils reveals how ancient host plant shifts and continental drift influenced the development of diverse insect-plant interactions through time.
If CHIP and mLOY do not significantly contribute to inflammation, atherosclerosis or myocardial infarction risk independently, CHIP may increase the risk of MI in men who do not carry mLOY.
An in vitro chemical screen with single-cell sequencing output leads to the identification of Metformin as an in vivo enhancer of Muller glia to neuron reprogramming in mice.
Somatic mutations frequently disrupt cleavage and polyadenylation signals in tumour suppressor genes in human cancers, likely contributing to tumour progression.
Amanda Mixon Blackwell, Yasaman Jami-Alahmadi ... Paul A Sigala
Plasmodium parasites have repurposed the heme oxygenase scaffold from its canonical heme-degrading function to fulfill an essential and adaptive role in gene expression within the apicoplast organelle.
Associative plasticity of proximal and distal granule cell inputs to Purkinje cells enables time dependent association of information from local and distant receptive fields.
Uncovering pharyngeal sour taste receptors in Drosophila melanogaster reveals a novel mechanism for detecting ingested carboxylic acids, expanding understanding of how insects internally sense and respond to appetitive tastants.
Time-related sequential activities in prefrontal cortex exhibit stable coding over weeks, while representations of other variables are dynamic, suggesting that neural sequences are consisted of unique group of neurons.
