Browse our Research Communication

Page 4 of 7
    1. Ecology
    2. Evolutionary Biology

    Quorums enable optimal pooling of independent judgements in biological systems

    James AR Marshall, Ralf HJM Kurvers ... Max Wolf
    Consideration of signal detection theory shows how decision ecology relates to optimal collective decisions, helping explain the prevalence of quorum-sensing in even the simplest collective systems, such as bacterial communities.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Defining host–pathogen interactions employing an artificial intelligence workflow

    Daniel Fisch, Artur Yakimovich ... Eva Frickel
    The application of deep learning fills a major gap in host–pathogen research providing for unbiased, multi-module high-throughput image analysis.
    1. Genetics and Genomics
    2. Neuroscience

    CNTN5-/+or EHMT2-/+human iPSC-derived neurons from individuals with autism develop hyperactive neuronal networks

    Eric Deneault, Muhammad Faheem ... Stephen W Scherer
    Autism-associated iPSC-derived neurons mutant in CNTN5 or EHMT2 are hyperactive.
    1. Neuroscience

    Real-time experimental control using network-based parallel processing

    Byounghoon Kim, Shobha Channabasappa Kenchappa ... Ari Rosenberg
    The Real-Time Experimental Control with Graphical User Interface (REC-GUI) framework can facilitate cutting-edge neuroscience research by providing precise experimental control using high-level programming environments familiar to many experimentalists.
    1. Cancer Biology

    FGF2-FGFR1 signaling regulates release of Leukemia-Protective exosomes from bone marrow stromal cells

    Nathalie Javidi-Sharifi, Jacqueline Martinez ... Elie Traer
    Inhibition of FGF2-FGFR1 signaling in bone marrow stroma attenuates secretion of FGF2-laden exosomes and subsequent protection of leukemia cells.
    1. Computational and Systems Biology
    2. Neuroscience

    Time preferences are reliable across time-horizons and verbal versus experiential tasks

    Evgeniya Lukinova, Yuyue Wang ... Jeffrey C Erlich
    People have stable time-preferences regardless of whether they are measured using a non-verbal experiential task, as is typical in animal experiments, or using a more traditional verbal task.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Listeria monocytogenes cell-to-cell spread in epithelia is heterogeneous and dominated by rare pioneer bacteria

    Fabian E Ortega, Elena F Koslover, Julie A Theriot
    The pathogenic bacterium Listeria monocytogenes spreads infection using a two-tiered strategy, where most bacteria spread locally but a few 'pioneers' move further, increasing the likelihood of a persistent infection.
    1. Physics of Living Systems

    A first order phase transition mechanism underlies protein aggregation in mammalian cells

    Arjun Narayanan, Anatoli Meriin ... Ibrahim I Cisse
    Quantitative single molecule and super resolution imaging in mammalian cells reveal a population of precursor aggregates describable by first order phase transition theory.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Molecular and topological reorganizations in mitochondrial architecture interplay during Bax-mediated steps of apoptosis

    Nicholas R Ader, Patrick C Hoffmann ... Wanda Kukulski
    Correlative microscopy and electron cryo-tomography on apoptotic HeLa cells reveal remodeling of outer and inner mitochondrial membranes, Bax cluster ultrastructure and ATP synthase reorganization in ruptured mitochondria.
    1. Developmental Biology

    Is it possible to reconstruct an accurate cell lineage using CRISPR recorders?

    Irepan Salvador-Martínez, Marco Grillo ... Maximilian J Telford
    Computer simulations reveal the potential and limitations of recently proposed CRISPR-based cell lineage recorders, and suggest how the recorders' design can be optimised to yield more accurate cell lineage trees.