Browse our Review Articles

PASC (post-acute sequelae of SARS-CoV-2 infection) is an enduring and debilitating illness caused by a persistent virus that promotes inflammation, coagulation, and autoimmunity complications in millions of patients initially diagnosed with COVID-19, but with no known standardized treatment regimen.

The mechanisms by which non-pathologic short tandem repeats normally influence gene expression and engender rapid genetic variation across phylogeny directly inform how expansions in these same repeats elicit neurological disease.

The primary rhythm generators controlling respiration are integrated in a much larger network of brain regions, including areas not typically considered to be respiratory control centers, and that allow respiration to be adapted to all forms of ongoing behavior.

As macrophages are involved in various aspects of non-small cell lung cancer development and progression it is crucial to develop appropriate 3D co-culture platforms for modeling immune cell-tumor cell interactions, leading to more efficacious macrophage-focused immunotherapies.

Hepatitis B virus infection is a neglected challenge among communities who are under-served by conventional models of healthcare, requiring enhanced interventions to reduce inequity.

Intracellular and interorgan skeletal crosstalk highlights integrative skeletal physiology.

The recent developments in large-scale machine learning, especially with the recent Transformer models, display much potential for solving computational problems within protein biology and outcompete traditional computational methods in many recent studies and benchmarks.

A synthesis of 20+ years of experimental studies on 'splitter cells' in the hippocampus reveals that signature properties of (1) temporal context models and (2) latent state inference are both needed to account for the data.

A mechanism is proposed that allows investigators to study interventions to delay onset of heart disease in patients suffering from chronic inflammatory disease with bone loss.

Zebrafish provide unique resources for the study of the tumor microenvironment.