Browse our Review Articles

Page 4 of 13
    1. Cancer Biology

    The role of macrophages in non-small cell lung cancer and advancements in 3D co-cultures

    Katarína Balážová, Hans Clevers, Antonella FM Dost
    As macrophages are involved in various aspects of non-small cell lung cancer development and progression it is crucial to develop appropriate 3D co-culture platforms for modeling immune cell-tumor cell interactions, leading to more efficacious macrophage-focused immunotherapies.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    The forgotten people: Hepatitis B virus (HBV) infection as a priority for the inclusion health agenda

    Emily Martyn, Sarah Eisen ... Philippa C Matthews
    Hepatitis B virus infection is a neglected challenge among communities who are under-served by conventional models of healthcare, requiring enhanced interventions to reduce inequity.
    1. Medicine

    Bone circuitry and interorgan skeletal crosstalk

    Mone Zaidi, Se-Min Kim ... Tony Yuen
    Intracellular and interorgan skeletal crosstalk highlights integrative skeletal physiology.
    1. Computational and Systems Biology

    Transformer-based deep learning for predicting protein properties in the life sciences

    Abel Chandra, Laura Tünnermann ... Regina Gratz
    The recent developments in large-scale machine learning, especially with the recent Transformer models, display much potential for solving computational problems within protein biology and outcompete traditional computational methods in many recent studies and benchmarks.
    1. Neuroscience

    Temporal context and latent state inference in the hippocampal splitter signal

    Éléonore Duvelle, Roddy M Grieves, Matthijs AA van der Meer
    A synthesis of 20+ years of experimental studies on 'splitter cells' in the hippocampus reveals that signature properties of (1) temporal context models and (2) latent state inference are both needed to account for the data.
    1. Medicine

    Is calcium a link between inflammatory bone resorption and heart disease?

    Gordon L Klein
    A mechanism is proposed that allows investigators to study interventions to delay onset of heart disease in patients suffering from chronic inflammatory disease with bone loss.
    1. Cancer Biology

    Shifting the focus of zebrafish toward a model of the tumor microenvironment

    Joshua M Weiss, Dianne Lumaquin-Yin ... Richard M White
    Zebrafish provide unique resources for the study of the tumor microenvironment.
    1. Developmental Biology

    Conservation of oocyte development in germline cysts from Drosophila to mouse

    Allan C Spradling, Wanbao Niu ... Bhawana Maurya
    Early oocyte development takes place in germline cysts and is strikingly conserved from Drosophila to mouse, reflecting common mechanisms that may help reverse aging and specify oocyte and early embryo polarity.
    1. Medicine

    Retinopathy of prematurity: Metabolic risk factors

    Zhongjie Fu, Anders K Nilsson ... Lois EH Smith
    An update for current knowledge gap in retinal metabolism after preterm birth and treatments for retinopathy of prematurity.
    1. Cell Biology

    Endosymbiotic selective pressure at the origin of eukaryotic cell biology

    Parth K Raval, Sriram G Garg, Sven B Gould
    All the characteristic traits of the eukaryotic cell, the basic unit of all macroscopic life, commenced to originate in a prokaryote as means to serve an endosymbiont today known as mitochondria.