Browse our Review Articles

Page 4 of 10
    1. Evolutionary Biology
    2. Neuroscience

    Proposing a neural framework for the evolution of elaborate courtship displays

    Ryan W Schwark, Matthew J Fuxjager, Marc F Schmidt
    The midbrain periaqueductal grey is a conserved mediator of elaborate courtship behavior in a range of vertebrate taxa, likely shaping how this behavior diversifies across the tree of life.
    1. Neuroscience

    Contractile force assessment methods for in vitro skeletal muscle tissues

    Camila Vesga-Castro, Javier Aldazabal ... Jacobo Paredes
    A standardized comparison of contractile force among in vitro muscle tissues across different platforms requires proper normalization with the contractile area and complementary morphological, maturation, and functional analysis to reduce variability and boost a new generation of engineered constructs.
    1. Medicine

    Post-acute sequelae of COVID-19: A metabolic perspective

    Philipp E Scherer, John P Kirwan, Clifford J Rosen
    The potential metabolic mechanisms that underly the growing prevalence of long COVID are explored and potential treatments discussed.
    1. Epidemiology and Global Health
    2. Evolutionary Biology

    Primate malarias as a model for cross-species parasite transmission

    Marina Voinson, Charles L Nunn, Amy Goldberg
    Ecological and evolutionary perspectives are critical to understand, predict, prevent, and treat malaria parasites that may spread to humans from our close primate relatives.
    1. Cell Biology

    Female fertility and the zona pellucida

    Paul M Wassarman, Eveline S Litscher
    The ZP is a viscoelastic ECM that provides stability for contacts between projections from the innermost cumulus cells and oocyte microvilli that pass through the ZP and form gap junctions shown to be essential for oocyte growth and follicle development.
    1. Biochemistry and Chemical Biology

    Immunomodulatory drug discovery from herbal medicines: Insights from organ-specific activity and xenobiotic defenses

    Jue Shi, Jui-Hsia Weng, Timothy J Mitchison
    Organ-selective drug action of traditional Chinese medicine that generates systemic immune mediators is proposed and reviewed as a novel mechanistic angle to develop new immunomodulatory drugs.
    1. Cell Biology

    The right time for senescence

    Diogo Paramos-de-Carvalho, Antonio Jacinto, Leonor Saúde
    A time-gated model is proposed to reconcile the transient vs. persistent biological activities of cellular senescence, in which 'time' seems to be the main orchestrator of the beneficial vs. detrimental effects of the senescent programme.
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    The influence of biological and lifestyle factors on circulating cell-free DNA in blood plasma

    Nicole Laurencia Yuwono, Kristina Warton, Caroline Elizabeth Ford
    Circulating cell-free DNA studies should control for participants' physical activity to avoid its confounding effect on total cell-free DNA level.
    1. Neuroscience

    Skipping ahead: A circuit for representing the past, present, and future

    Jennifer C Robinson, Mark P Brandon
    A circuit between the hippocampus, nucleus reunions, and prefrontal cortex organizes information about the past, present, and future into alternating theta sequences.
    1. Developmental Biology

    Y chromosome functions in mammalian spermatogenesis

    Jeremie Subrini, James Turner
    The mammalian Y chromosome has become specialised for male fertility, but exact functions of individual Y genes remain poorly understood, a knowledge gap that new approaches can bridge.