Vibha Kumra Ahnlide, Johannes Kumra Ahnlide ... Pontus Nordenfelt
A method to carefully measure the molecular distance between a site of interest and a reference surface by the repeated acquisition of the two image channels followed by the statistical calculation of the relative difference.
Han-Xiong Bear Zhang, Laurel Heckman ... Bruce P Bean
The phytocannabinoid cannabidiol, an antiepileptic agent whose molecular targets are unclear, was found to potently enhance current carried by cloned human Kv7.2/7.3 channels and native M-current in mouse and rat neurons.
Temperature variation caused by heatwaves and diurnal fluctuations has distinct effects on host and pathogen traits at different mean temperatures, leading to large and unexpected differences in disease burden making the impact of global warming on diseases hard to predict.
Michaël Elbaz, Amalia Callado Perez ... Martin Deschenes
A predominant but less studied sensory pathway for both vibrissa self-motion and touch inputs is shown to broadcast broadly to brainstem regions involved in regulation of autonomic functions as well as forebrain regions involved in expression of emotional reactions.
Saige Rutherford, Charlotte Fraza ... Andre F Marquand
During an individual's lifetime, their brain undergoes a unique transformation that we have precisely mapped across thousands of people to create and share reference growth charts of the human brain's lifespan which allow for single subject exploration and inference.
An in silico analysis of gap junction proteins supports the hypothesis that connexins replaced the primordial innexins in chordate gap junctions due to an evolutionary bottleneck.
James A Timmons, Andrew Anighoro ... Stuart M Phillips
Optimising the use of transcriptomics enables screening of thousands of compounds and illustrates an approach that yields quantitative pharmacology at the single-gene and pathway level.
