Browse our Tools and Resources

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    1. Genetics and Genomics
    2. Neuroscience

    A genetic, genomic, and computational resource for exploring neural circuit function

    Fred P Davis, Aljoscha Nern ... Gilbert L Henry
    Transcriptomes of cells in the Drosophila visual system combined with anatomy and other information reveal new functional insight into the visual circuit.
    1. Cancer Biology
    2. Cell Biology

    Junction Mapper is a novel computer vision tool to decipher cell–cell contact phenotypes

    Helena Brezovjakova, Chris Tomlinson ... Vania MM Braga
    Junction Mapper is a powerful new semi-automated software that provides a fingerprint of cell–cell contact morphometry and receptor density alterations.
    1. Microbiology and Infectious Disease

    Dynamic post-translational modification profiling of Mycobacterium tuberculosis-infected primary macrophages

    Jonathan M Budzik, Danielle L Swaney ... Jeffery S Cox
    Measurement of post-translational modifications in primary macrophages infected with Mtb revealed phosphorylation of TAX1BP1, an autophagy receptor that enables full maturation of the Mtb autophagosome.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    Quantitative analysis of 1300-nm three-photon calcium imaging in the mouse brain

    Tianyu Wang, Chunyan Wu ... Chris Xu
    Quantitative experiments and analysis determine the limit of excitation power of 1300-nm three-photon microscopy, and the imaging depth where three-photon outperforms two-photon for calcium imaging in the mouse brain.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    In vivo single-cell lineage tracing in zebrafish using high-resolution infrared laser-mediated gene induction microscopy

    Sicong He, Ye Tian ... Jianan Y Qu
    Infrared laser-mediated gene induction microscopy enables precise single-cell labeling in various tissues of zebrafish, and in vivo visualized single-cell lineage tracing reveals the lineage heterogeneity in hematopoietic endothelial cells.
    1. Neuroscience

    Human Neocortical Neurosolver (HNN), a new software tool for interpreting the cellular and network origin of human MEG/EEG data

    Samuel A Neymotin, Dylan S Daniels ... Stephanie R Jones
    Human Neocortical Neurosolver is a new user-friendly software tool for researchers to develop and test hypotheses on cellular/circuit origins of human MEG/EEG signals using a biophysical model.
    1. Cell Biology
    2. Plant Biology

    Imaging plant germline differentiation within Arabidopsis flowers by light sheet microscopy

    Sona Valuchova, Pavlina Mikulkova ... Karel Riha
    Light sheet microscopy was used to establish a method for live imaging of cellular events within Arabidopsis flower and for constructing a 3D model of flower at subcellular resolution.
    1. Immunology and Inflammation

    High-dimensional analysis of intestinal immune cells during helminth infection

    Laura Ferrer-Font, Palak Mehta ... Johannes U Mayer
    A systematic optimization of intestinal digestion protocols allows for the isolation and high-dimensional flow cytometric analysis of intestinal immune cells during murine helminth infection.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    CNApp, a tool for the quantification of copy number alterations and integrative analysis revealing clinical implications

    Sebastià Franch-Expósito, Laia Bassaganyas ... Jordi Camps
    CNApp is a novel and unique web-based software that enables the performance of comprehensive and integrative analysis of genomic copy number alterations to uncover new associations with patient-oriented relevance.
    1. Stem Cells and Regenerative Medicine

    Transcriptional landscape of myogenesis from human pluripotent stem cells reveals a key role of TWIST1 in maintenance of skeletal muscle progenitors

    In Young Choi, Hotae Lim ... Gabsang Lee
    Using multiple genetic reporter system in human pluripotent stem cells, a transcriptional database for human early myogenesis has been established.