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Page 187 of 1,878
    1. Cancer Biology

    Inhibition of p38-MK2 pathway enhances the efficacy of microtubule inhibitors in breast cancer cells

    Yu-Chia Chen, Mamoru Takada ... Aussie Suzuki
    Inhibiting the p38 MAPK-MK2 signaling pathway significantly boosts the efficacy of microtubule-targeting agents specifically in breast cancer cells, highlighting a potential new therapeutic strategy for improved cancer treatment.
    1. Neuroscience

    AgRP1 modulates breeding season-dependent feeding behavior in female medaka

    Yurika Tagui, Shingo Takeda ... Chie Umatani
    AgRP1, a feeding-related peptide in the brain, facilitates feeding behavior of female medaka in the breeding season, which is important for reproductive success.
    1. Neuroscience

    Transdiagnostic compulsivity is associated with reduced reminder setting, only partially attributable to overconfidence

    Annika Boldt, Celine Ann Fox ... Sam Gilbert
    Highly compulsive individuals set fewer reminders, partly due to inflated confidence and partly due to compulsivity itself, revealing how individual differences shape the strategic reminder use in daily life.
    1. Epidemiology and Global Health
    2. Neuroscience

    Menopausal hormone therapy and the female brain: Leveraging neuroimaging and prescription registry data from the UK Biobank cohort

    Claudia Barth, Liisa AM Galea ... Ann-Marie G de Lange
    A big-data approach shows the effects of menopausal hormone therapy on female brain health might vary depending on the duration of use and history of gynaecological surgery.
    1. Cell Biology
    2. Developmental Biology

    Mutations that prevent phosphorylation of the BMP4 prodomain impair proteolytic maturation of homodimers leading to lethality in mice

    Hyung-Seok Kim, Mary L Sanchez ... Jan L Christian
    Phosphorylation of the BMP4 prodomain is required for proteolytic activation of BMP4 homodimers, but not BMP4/7 heterodimers.
    1. Cell Biology

    Force transmission through the inner kinetochore is enhanced by centromeric DNA sequences

    Elise Miedlar, Grace E Hamilton ... Trisha N Davis
    Biochemical reconstitution and laser trapping show that centromeric DNA sequences are important for the transmission of microtubule-based forces to chromosomes.
    1. Microbiology and Infectious Disease

    Identifying a novel mechanism of L-leucine uptake in Mycobacterium tuberculosis using a chemical genomic approach

    Nisheeth Agarwal, Himanshu Gogoi ... Bappaditya Dey
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Microbiology and Infectious Disease

    Type I interferon responses contribute to immune protection against mycobacterial infection

    Andrea Szydlo-Shein, Blanca Sanz-Magallón Duque de Estrada ... Gillian S Tomlinson
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Immunology and Inflammation

    Temperature-based MHC class-I multimer peptide exchange for human HLA-A, B and C

    Cilia R Pothast, Ian Derksen ... Ferenc A Scheeren
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Developmental Biology

    Integrated transcriptomic analysis of human induced pluripotent stem cell-derived osteogenic differentiation reveals a regulatory role of KLF16

    Ying Ru, Meng Ma ... Meng Wu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
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