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Page 190 of 1,878
    1. Ecology
    2. Evolutionary Biology

    Rapid riparian ecosystem recovery in low-latitudinal North China following the end-Permian mass extinction

    Wenwei Guo, Li Tian ... Jinnan Tong
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Cancer Biology
    2. Medicine

    Molecular feature-based classification of retroperitoneal liposarcoma: a prospective cohort study

    Mengmeng Xiao, Xiangji Li ... Li Min
    Identification of two molecularly distinct retroperitoneal liposarcoma subtypes, stratifiable via LEP and PTTG1 biomarkers, enables prognosis prediction and informs precision surgical strategies to improve clinical outcomes.
    1. Developmental Biology
    2. Neuroscience

    Commissureless acts as a substrate adapter in a conserved Nedd4 E3 ubiquitin ligase pathway to promote axon growth across the midline

    Kelly G Sullivan, Greg J Bashaw
    Commissureless works with the Nedd4 E3 ubiquitin ligase to transiently degrade the Robo1 receptor to allow commissural axons to cross the midline.
    Version of Record
    Research Article
    • Fundamental
    • Compelling
    • Convincing
    1. Neuroscience

    Network segregation is associated with processing speed in the cognitively healthy oldest-old

    Sara A Nolin, Mary E Faulkner ... Kristina M Visscher
    Greater differentiation of brain networks is a hallmark of good cognitive functioning among individuals who have avoided neurodegenerative disease and live longer than a typical human lifespan.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Somatic hypermutation patterns in immunoglobulin variable regions are established independently of the local transcriptional landscape

    Ursula E Schoeberl, Johanna Fitz ... Rushad Pavri
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Towards a unified molecular mechanism for ligand-dependent activation of NR4A-RXR heterodimers

    Xiaoyu Yu, Yuanjun He ... Douglas J Kojetin
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Computational and Systems Biology

    Unsupervised reference-free inference reveals unrecognized regulated transcriptomic complexity in human single cells

    Roozbeh Dehghannasiri, George Henderson ... Julia Salzman
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Immunology and Inflammation

    T-follicular helper cell profiles differ by malaria antigen and for children compared to adults

    Catherine Suzanne Forconi, Christina Nixon ... Ann M Moormann
    Pf-GARP antigen seems to be a better malaria vaccine candidate compared to PfSEA-1A, as it triggered the activation of cTFH17, involved in the maintenance of memory antibody responses in adults.
    1. Microbiology and Infectious Disease

    Wag31, a membrane tether, is crucial for lipid homeostasis in mycobacteria

    Yogita Kapoor, Himani Khurana ... Vinay Kumar Nandicoori
    A novel function of Wag31 in membrane tethering and molecular dissection of the functions of its N- and C-terminal domains.
    1. Neuroscience

    Subcortical correlates of consciousness with human single neuron recordings

    Michael Pereira, Nathan Faivre ... Olaf Blanke
    Subcortical brain structures contain neurons encoding subjective reports of stimulus detection in human participants, suggesting a role for conscious perception.
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