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Head and body orientation cues are integrated by macaque superior temporal sulcus neurons, with stronger integration for upright monkey images.

Drugs are identified that unmask molecular origins of certain neuronal potassium currents, enabling functional analysis of previously indistinguishable potassium channel subtypes.

New protein-protein docking algorithm combining deep learning (AlphaFold2) and physics (Rosetta and enhanced sampling) achieves high success rates.

IFN-β-induced WTAP phase transition bridges STAT1 and MTC, which orchestrates m⁶A dynamics on ISG mRNAs to suppress excessive immune response and sustain immune homeostasis.

Precise protein quality control in the endoplasmic reticulum is crucial for Cryptococcus neoformans pathogenicity by modulating glycoprotein processing and extracellular vesicle-mediated transport of virulence factors.

A single protein can switch cellular behaviors from protrusion to retraction based on its concentration and dynamics, revealing a novel mechanism for controlling antagonistic phenotypes in cell signaling.

Targeting EMC10 restores neuronal function in 22q11.2DS patient-derived neurons and reverses cognitive deficits in adult mice, highlighting its potential as a therapeutic strategy for mitigating disease-related cognitive impairments.

Nutritional adaptations in Leishmania donovani enable persistent antimony resistance and reduced Amphotericin-B effectiveness by selectively exploiting host lipids and limiting cholesterol mobilization.

Trophoblast organoids recapitulate syncytiotrophoblast nuclear heterogeneity and reveal environment-dependent gene regulation critical for placental hormone production and differentiation.

Household clustering and seasonal parasite dynamics highlight the need to target asymptomatic carriers for community-based malaria elimination strategies.