Functional neural circuit dissection identifies sensorimotor responses to noxious cold in Drosophila larvae revealing complex mechanisms by which nervous systems sense and respond to cold.
BCAS2 directly binds to the Armadillo repeats 9–12 of β-catenin via the coiled-coil domains, sequestering β-catenin within the nucleus and thereby promoting Wnt signaling during primitive hematopoiesis.
Parham Mostame, Jonathan Wirsich ... Sepideh Sadaghiani
Parallel connectome trajectories unfold asynchronously across timescales, sustaining a multiplex of functionally distinct brain networks operating at different speeds.
Hannes P Saal, Ingvars Birznieks, Roland S Johansson
Fingertip tactile neurons collectively encode the skin's viscoelastic state alongside current touch, potentially enabling the brain to better interpret forces during manipulation.
SCellBOW is a language model-based scRNA-seq analysis method that identifies malignant cell subpopulations and infers marker-free survival risks using transfer learning.