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    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Endothelial cell signature in muscle stem cells validated by VEGFA-FLT1-AKT1 axis promoting survival of muscle stem cell

    Mayank Verma, Yoko Asakura ... Atsushi Asakura
    Bulk and single-cell RNA-seq data demonstrated that muscle stem cells express low levels of canonical endothelial cell markers, including VEGFA receptors, and VEGFA-FLT1 pathway has a drastic effect on muscle stem cell survival through AKT1 in vitro and in vivo.
    1. Cell Biology

    Mechanotransductive feedback control of endothelial cell motility and vascular morphogenesis

    Devon E. Mason, Paula Camacho ... Joel D. Boerckel
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cancer Biology

    Timing of treatment shapes the path to androgen receptor signaling inhibitor resistance in prostate cancer

    Eugine Lee, Zeda Zhang ... Charles L. Sawyers
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience

    Neurons in the ventral striatopallidal complex modulate lateral hypothalamic orexin/hypocretin neuron activity: Implications for reward-seeking

    Caitlin S. Mitchell, Aida Mohammadkhani ... Christopher V. Dayas
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Convincing
    1. Ecology

    Human disturbance increases spatiotemporal associations among mountain forest terrestrial mammal species

    Xueyou Li, William V Bleisch ... Xue-Long Jiang
    Human disturbance can push mammals together into more frequent encounters and associations.
    1. Cell Biology

    Editing of endogenous tubulins reveals varying effects of tubulin posttranslational modifications on axonal growth and regeneration

    Yu-Ming Lu, Shan Yan ... Chaogu Zheng
    Posttranslational modifications of tubulins regulate axonal growth and regeneration by controlling the stabilities of microtubules or modulating their interactions with microtubule-associated proteins.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Heparan sulfate-dependent phase separation of CCL5 and its chemotactic activity

    Xiaolin Yu, Guangfei Duan ... Shi-Zhong Luo
    A biochemical approach shows co-phase separation of CCL5 with heparan sulfate establishes a specific chemokine concentration gradient for chemotactic activity.
    1. Epidemiology and Global Health
    2. Cancer Biology

    Conditional Survival and Nomogram for Elderly Non-Metastatic Colon Cancer Patients Following Colectomy

    Yadong Gao, Huimin Wang ... Jianwei Qiu
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete