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Page 281 of 1,781
    1. Cell Biology

    BMP signaling maintains auricular chondrocyte identity and prevents microtia development by inhibiting protein kinase A

    Ruichen Yang, Hongshang Chu ... Baojie Li
    Uncovering a new function of BMP signaling and enhancing our comprehension of the pathogenesis of microtia.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Experimental evolution for the recovery of growth loss due to genome reduction

    Kenya Hitomi, Yoichiro Ishii, Bei-Wen Ying
    Diversified genetic and transcriptional changes in parallel evolved Escherichia coli populations for improved growth revealed that the evolution complementing genome reduction was like all roads leading to Rome.
    1. Medicine

    Fungal–bacteria interactions provide shelter for bacteria in Caesarean section scar diverticulum

    Peigen Chen, Haicheng Chen ... Xing Yang
    Local abnormal fungi in Caesarean section scar diverticulum can affect the abundance of bacteria through specific metabolites, thereby destroying the stability of bacteria and the entire microbial community.
    1. Genetics and Genomics

    Mono-methylated histones control PARP-1 in chromatin and transcription

    Gbolahan Bamgbose, Guillaume Bordet ... Alexei Tulin
    Genome-wide PARP-1 binding analysis advances the understanding of molecular mechanisms governing gene regulation in response to developmental cues and environmental stressors.
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    Context-Aware Amino Acid Embedding Advances Analysis of TCR-Epitope Interactions

    Pengfei Zhang, Seojin Bang ... Heewook Lee
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Medicine
    2. Stem Cells and Regenerative Medicine

    Scalable, optically-responsive human neuromuscular junction model reveals convergent mechanisms of synaptic dysfunction in familial ALS

    Daniel Chen, Polyxeni Philippidou ... Helen C. Miranda
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cancer Biology
    2. Epidemiology and Global Health

    Associations of combined phenotypic aging and genetic risk with incident cancer: A prospective cohort study

    Lijun Bian, Zhimin Ma ... Guangfu Jin
    Older PhenoAge was consistently related to an increased risk of incident cancer with adjustment for chronological age and the aging process could be retarded by adherence to a healthy lifestyle.
    1. Neuroscience

    Aberrant cortical activity, functional connectivity, and neural assembly architecture after photothrombotic stroke in mice

    Mischa Vance Bandet, Ian Robert Winship
    Longitudinal calcium imaging in awake mice after stroke suggests impairments in neuronal activity, functional connectivity, and neural assembly architecture is transient and limited to cortex immediately adjacent to the stroke.
    1. Evolutionary Biology

    Synthetic analysis of trophic diversity and evolution in Enantiornithes with new insights from Bohaiornithidae

    Case Vincent Miller, Jen A Bright ... Michael Pittman
    Enantiornithine birds reached similar dietary diversity to modern birds in a similar amount of time many millions of years earlier, but how exactly they did that requires further research.
    1. Cancer Biology
    2. Cell Biology

    Loss of tumor suppressor TMEM127 drives RET-mediated transformation through disrupted membrane dynamics

    Timothy J Walker, Eduardo Reyes-Alvarez ... Lois M Mulligan
    TMEM127 depletion alters membrane dynamics, promoting cell surface accumulation and constitutive activity of growth factor receptors, and ultimately providing a novel paradigm for oncogenesis through aberrant receptor localization and signaling.