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Primary endothelial cell cultures contain markedly heterogeneous cell subtypes that exhibit distinct molecular responses to disease-relevant exposures.

Structural insights into the orthosteric inhibition and subtype specificity of P2X receptors by classical P2X antagonists facilitate the rational design of novel competitive antagonists for P2X receptors.

Individuals with higher blood levels of omega-3 and omega-6 fatty acids, especially omega-3, are less likely to die, either from any cause, cancer or cardiovascular disease.

Structural representations of sentences generated by deep language models correlate with human listeners' behaviours and neural activity, providing a quantifiable framework to uncover the neural dynamics underpinning incremental speech comprehension.

Cell type-specific effects of antipsychotic drugs in cortex could provide a basis for a functional screen of antipsychotic efficacy.

The existence of a slow-moving zone around the transcription site may unify conflicting models of co-transcriptional versus post-transcriptional mRNA splicing.

Anatomical tracing, in combination with a genetic ablation approach, identifies a critical maturation period for neocortex to dorsal raphe afferents pivotal for the development of behavioral persistence over adolescence in mice.

ROCK and the actomyosin network are essential for multiple aspects of sea urchin skeletogenesis, suggesting an independent deployment of these factors in biomineralization across Eukaryotes.

Results show that STAT3 and KRAS jointly regulate oncogenic dependency of mutant KRAS cancer cells.