Browse the latest research

Microfluidic methods are used to quantitatively probe single yeast cells' response to either simultaneous or sequential stresses, revealing the dynamic interplay between two antagonistic inputs, osmotic stress and glucose starvation.

The ~20,000 origins of replication in human cell lines that are reproducibly identified by multiple techniques in multiple cell lines are distant from known origin recognition complex and MCM2-7-binding sites.

A majority of transcribed transposons during aging are derived from transcriptional defects, most notably intron retention and transcriptional readthrough.

Fibroblast growth factor (FGF) ligands exhibit different preferences for signaling cascades triggered through FGFR1, a receptor which is critical for skeletal development, and these differences likely contribute to the amazing complexity of developmental processes.

This sesquiterpene hormone likely acted as a morphogenesis-to-differentiation switch in archaic embryos before it evolved its postembryonic function as the status quo regulator of insect metamorphosis.

Binocular combination of monocular neuronal responses involves response suppression for neurons more preferring one eye and response enhancement for neurons more preferring both eyes in macaque V1.

Optogenetic manipulation and photometry recordings in the lateral hypothalamus show how interactions between dopamine and orexin systems underlie reward expectation revealing dopaminergic modulation of orexinergic activity via D2 receptors.

A CRISPR knock-in approach enables the efficient generation of tissue-specific LexA and QF driver lines which can simultaneously control gene expression in multiple tissues.

Spatial mapping serves as a cognitive scaffold for acquiring abstract conceptual invariances across sensory domains, shedding light on the mechanisms of human learning.

Vitamin D regulates two human chromosomal loci, Chr17q12-21.1 and Chr17q21.2, that are associated with autoimmune and chronic inflammatory diseases.