Studies in murine model identify hepatic Rela-Stat3 network as a potential driver of gut inflammation and a novel therapeutic target for inflammatory bowel disease, offering new insights into liver-gut crosstalk.
Semaphorin7A sculpts the collective arbor architecture of the lateral line nerve and facilitates neural contacts with the hair cells for synaptogenesis during neuromast development in the zebrafish.
Electrophysiological recordings and optogenetics reveal how the dorsal periaqueductal gray and basolateral amygdala interact in antipredatory responses, with a potential intermediary role for the midline thalamus.
Harshavardhan Lingegowda, Katherine B Zutautas ... Chandrakant Tayade
Cannabinoid receptors CNR1 and CNR2 play distinct roles in endometriosis pathogenesis, potentially contributing to disease initiation and progression through differential modulation of T cell function and the lesion microenvironment.
Separating behaviorally relevant signals from irrelevant signals reveals that neural signals previously considered to contain little information encode rich information and suggests that linear readout may be performed in motor cortex.
Transcriptomic analyses of Malabar grouper show pathways known to be involved in metamorphosis are also upregulated at an early stage of larval development, suggesting an additional function during early development.
Whole-transcriptomic profiling of circulating small extracellular vesicle RNA facilitates the detection of T1a stage colorectal cancer and precancerous advanced adenoma.
