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Behavioral electrophysiology and optogenetics studies reveal that projections from the anterior insula to the medial thalamus mitigate fear, while projections to the amygdala promote fear.

The 3R framework outlines three fundamental processes in motor learning and provides a novel perspective on understanding how we acquire, adapt, and retain complex motor skills.

A comprehensive exploration of α-synuclein (αS) aggregation dynamics from both macroscopic and microscopic perspectives uncovers the intricate mechanisms underlying crowder and salt-induced intensification of αS self-aggregation.

Kinase conformation reporters reveal how protein kinase activity conformations are influenced by regulatory protein interactions, patient mutations, and cellular drug binding, aiding in systematically anticipating treatment efficacy and designing patient-tailored therapies.

Strong out of distribution generalization using an attentional mechanism over grid cell code inspired by determinantal point processes.

Targeting the interaction between the kidneys and brain may increase the efficiency of SGLT2 inhibitors to better manage type 2 diabetes.

Enriching amphibian, Xenopus laevis, cutaneous mast cells confers protection against Batrachochytrium dendrobatidis chytrid fungus infections.

P-Rex1 adopts an inactive, compact conformation that is stabilized by an abundant intracellular molecule and undergoes dynamic changes to extend upon encountering signaling phospholipids in membranes.