Browse the latest research

Page 495 of 1,892
    1. Cell Biology
    2. Microbiology and Infectious Disease

    A CRISPR-based rapid DNA repositioning strategy and the early intranuclear life of HSV-1

    Juan Xiang, Chaoyang Fan ... Pei Xu
    An inducible two-component CRISPR-based platform that rapidly repositions HSV-1 genomes to the nuclear edge unveils intranuclear space heterogeneity for the incoming viral genomes and dynamic stages of the host-virus interplay during early infection.
    1. Neuroscience

    Rodent ultrasonic vocal interaction resolved with millimeter precision using hybrid beamforming

    Max L Sterling, Ruben Teunisse, Bernhard Englitz
    The accuracy of the Hybrid Vocalization Localizer (HyVL) brings a revolution to the study of social vocalizations of rodents and other animals, where vocalizations often occur in close proximity, and will empower downstream analysis of sequence and semantic analyses.
    1. Developmental Biology
    2. Neuroscience

    The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genes

    Xiong Yang, Rong Wan ... Ke Tang
    Two intrinsic factors converge to govern the differentiation and integration of distinct characteristics of the hippocampus in mice.
    1. Neuroscience

    Different rules for binocular combination of luminance flicker in cortical and subcortical pathways

    Federico G Segala, Aurelio Bruno ... Daniel H Baker
    Binocular combination of luminance signals exhibits strong interocular suppression in pathways governing the pupil response, and weak interocular suppression in cortical pathways subserving perception.
    1. Neuroscience

    Multiple dynamic interactions from basal ganglia direct and indirect pathways mediate action selection

    Hao Li, Xin Jin
    Experimental data and computational simulations reveal a new functional model, that is 'Triple-control' for the basal ganglia pathways in action selection.
    1. Developmental Biology
    2. Evolutionary Biology

    Gene expression mapping of the neuroectoderm across phyla – conservation and divergence of early brain anlagen between insects and vertebrates

    Nico Posnien, Vera S Hunnekuhl, Gregor Bucher
    Hypotheses on brain homologies between insects and vertebrates are tested by comparing gene expression patterns from flies and beetles with those from vertebrates at early neuroectoderm stages.
    1. Neuroscience

    Long-timescale anti-directional rotation in Drosophila optomotor behavior

    Omer Mano, Minseung Choi ... Damon A Clark
    When walking flies are shown bright, high-contrast rotating visual stimuli, they begin to turn in the direction opposite the rotation, showing that optomotor turning behavior contains rich, stimulus-dependent dynamics.
    1. Plant Biology

    Tetraose steroidal glycoalkaloids from potato provide resistance against Alternaria solani and Colorado potato beetle

    Pieter J Wolters, Doret Wouters ... Vivianne GAA Vleeshouwers
    Chemical modifications of steroidal glycoalkaloids of potato can cause strong resistance against the necrotrophic early blight fungus as well as the Colorado potato beetle.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    A pH-sensitive switch activates virulence in Salmonella

    Dasvit Shetty, Linda J Kenney
    A single conserved residue – histidine 12 – confers pH-sensitive DNA binding to the Salmonella Typhimurium SPI-2 transcriptional regulator SsrB, thereby regulating Salmonella virulence.
    1. Cell Biology

    Mitochondrial defects caused by PARL deficiency lead to arrested spermatogenesis and ferroptosis

    Enrico Radaelli, Charles-Antoine Assenmacher ... Marco Spinazzi
    Mitochondrial functional and structural defects caused by PARL deficiency lead to arrested spermatogenesis and germ cell ferroptosis.