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    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Modeling metabolic disease susceptibility and resilience in genetically diverse mice

    Candice N Baker, Jeffrey M Harder ... Gary A Churchill
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Compelling
    1. Neuroscience

    Challenges in Replay Detection by TDLM in Post-Encoding Resting State

    Simon Kern, Juliane Nagel ... Gordon Feld
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cell Biology

    Large-scale identification of plasma membrane repair proteins revealed spatiotemporal cellular responses to plasma membrane damage

    Yuta Yamazaki, Keiko Kono
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology

    Cellular characterization of the mouse collecting lymphatic vessels reveals that lymphatic muscle cells are the innate pacemaker cells

    Scott D Zawieja, Grace A Pea ... Michael J Davis
    Lymphatic muscle cells, but not CD34+ adventitial cells, exhibited pacemaker behaviors including pressure-dependent depolarization, pressure-dependent calcium mobilization during diastole, and propagated contraction waves induced by focal, optogenetic depolarization via channel rhodopsin2.
    1. Neuroscience

    Mining the neuroimaging literature

    Jérome Dockès, Kendra M Oudyk ... Jean-Baptiste Poline
    New tools for literature mining, such as automated analysis of the research literature, are accessible, scalable, and reliable.
    1. Cancer Biology
    2. Developmental Biology

    Dissecting infant leukemia developmental origins with a hemogenic gastruloid model

    Denise Ragusa, Chun Wai Suen ... Cristina Pina
    The hemogenic gastruloid model of embryonic blood development captures multi-wave haematopoiesis and enables interrogation of infant leukaemia cell-of-origin.
    1. Plant Biology

    Molecular architecture of thylakoid membranes within intact spinach chloroplasts

    Wojciech Wietrzynski, Lorenz Lamm ... Benjamin D Engel
    Cryo-electron tomography reveals plant photosynthetic membranes with single-complex precision, supporting a simple two-domain model of membrane organization.
    1. Neuroscience

    Dynamic estimation of the attentional field from visual cortical activity

    Ilona M Bloem, Leah Bakst ... Sam Ling
    Visuocortical activity in humans reveals that the spatial focus of covert attention flexibly shifts and expands in accordance with task demands.
    1. Evolutionary Biology

    Structural evolution of nitrogenase over 3 billion years

    Bruno Cuevas Zuviría, Franka Detemple ... Betül Kaçar
    Structural reconstruction of thousands of ancient nitrogenases through Earth’s history uncovers architectural constraints that shaped their evolution under global environmental transitions.
    1. Immunology and Inflammation

    Xcr1+ type 1 conventional dendritic cells are essential mediators for atherosclerosis progression

    Tianhan Li, Liaoxun Lu ... Lichen Zhang
    Using Xcr1Cre-Gfp Rosa26LSL-DTA Apoe–/– model and Xcl1–/– Apoe–/– mouse model reveal an essential non-redundant role for the XCL1-XCR1 axis in cDC1-mediated atherogenesis.
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