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Page 8 of 1,856
    1. Neuroscience

    Distinct goal location beta frequency dynamics in hippocampus and prefrontal cortex across learning

    Glingna Wang, Nan Zhou ... Jai Y Yu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Computational and Systems Biology
    2. Neuroscience

    Biologically informed cortical models predict optogenetic perturbations

    Christos Sourmpis, Carl CH Petersen ... Guillaume Bellec
    Multi area RNN models fitted to in-vivo cortical activity predict behavioral changes induced by optogenetic perturbations, if biologically informed connectivity constraints on the optogenetically targeted inhibitory neurons are applied.
    1. Microbiology and Infectious Disease

    Stratification of viral shedding patterns in saliva of COVID-19 patients

    Hyeongki Park, Yoshimura Raiki ... Taiga Miyazaki
    Distinct patterns of SARS-CoV-2 viral dynamics in saliva reveal heterogeneity that cannot be sufficiently explained by conventional clinical characteristics or microRNA profiles alone.
    1. Computational and Systems Biology

    Targeted computational design of an interleukin-7 superkine with enhanced folding efficiency and immunotherapeutic efficacy

    See-Khai Lim, Wen-Ching Lin ... Kurt Yun Mou
    Targeted computational redesign of an IL-7 superkine with enhanced folding efficiency and receptor affinity demonstrates superior immune-stimulatory and antitumor activity over wild-type IL-7.
    1. Developmental Biology

    Glial betaPix is essential for blood vessel development in the zebrafish brain

    Shihching Chiu, Qinchao Zhou ... Jing-Wei Xiong
    The glial-specific role of betaPix during cerebral blood vessel development has been revealed by establishing a new betaPix conditional trap allele in zebrafish.
    1. Neuroscience

    Disruption of theta-timescale spiking impairs learning but spares hippocampal replay

    Abhilasha Joshi, Alison E Comrie ... Loren M Frank
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Developmental Biology

    map3k1 is required for spatial restriction of progenitor differentiation in planarians

    Bryanna Isela-Inez Canales, Hunter O King, Peter W Reddien
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology

    SLC4A1 mutations that cause distal renal tubular acidosis alter cytoplasmic pH and cellular autophagy

    Grace Essuman, Midhat Rizvi ... Emmanuelle Cordat
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Genetics and Genomics
    2. Epidemiology and Global Health

    Heterogenous associations of polygenic indices of 35 traits with mortality

    Hannu Lahtinen, Jaakko Kaprio ... Pekka Martikainen
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Accessibility of the unstructured α-tubulin C-terminal tail is controlled by microtubule lattice conformation

    Takashi Hotta, Morgan L Pimm ... Kristen J Verhey
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
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