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    1. Neuroscience

    Hypothalamic deiodinase type-3 establishes the period of circannual interval timing in mammals

    Calum Stewart, T Adam Liddle ... Tyler J Stevenson
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    Phase-specific premotor inhibition modulates leech rhythmic motor output

    Martina Radice, Agustín Sanchez Merlinsky ... Lidia Szczupak
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Ecology
    2. Physics of Living Systems

    Colony demographics shape nest construction in Camponotus fellah ants

    Harikrishnan Rajendran, Roi Weinberger ... Ofer Feinerman
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Cancer Biology

    PA28γ promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP

    Jiongke Wang, Yujie Shi ... Qianming Chen
    The promotion of C1QBP accumulation by PA28γ leads to the malignant progression of tumor by affecting mitochondrial function, which could be a launch pad for therapeutic intervention of tumor development.
    1. Neuroscience

    A stochastic explanation for observed local-to-global foraging states in Caenorhabditis elegans

    Andrew Margolis, Andrew Gordus
    Changes in internal state for stochastic behaviors can be more easily explained by a stochastic model with no state change.
    Version of Record
    Short Report
    • Valuable
    • Convincing
    1. Genetics and Genomics
    2. Neuroscience

    The C. elegans gustatory receptor homolog LITE-1 is a chemoreceptor required for diacetyl avoidance

    Alan Koh, Eduard Bokman ... André EX Brown
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Atypical collective oscillatory activity in cardiac tissue uncovered by optogenetics

    Alexander S Teplenin, Nina N Kudryashova ... Tim De Coster
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Altered reactivity to threatening stimuli in Drosophila models of Parkinson’s disease, revealed by a trial-based assay

    Márton Kajtor, Viktor András Billes ... Balázs Hangya
    An inexpensive, scalable trial-based behavioral assay revealed quantitative difference in fruit flies' escape behavior across different genetic models of neurodegeneration.
    1. Genetics and Genomics

    Specific modulation of CRISPR transcriptional activators through RNA-sensing guide RNAs in mammalian cells and zebrafish embryos

    Oana Pelea, Sarah Mayes ... Tatjana Sauka-Spengler
    RNA-sensing guide RNAs provide a programmable platform for conditional, sequence-specific activation of CRISPR-Cas9 upon RNA detection in diverse biological contexts.
    1. Cell Biology

    N-cadherin mechanosensing in ovarian follicles controls oocyte maturation and ovulation

    Alaknanda Emery, Orest W Blaschuk ... Darryl L Russell
    A critical role for N-cadherin in ovarian follicular development and ovulation is demonstrated with inhibitors or knockout of N-cadherin shown to inhibit ovulation by blocking mechanotransduction of ovulatory genes.
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