Cell Biology

Latest articles

1. 1. Cell Biology

   Single-cell lineage tracing identifies hemogenic endothelial cells in the adult mouse bone marrow

   Jing-Xin Feng, Mei-Ting Yang ... Giovanna Tosato
2. 1. Cell Biology

   Large-scale identification of plasma membrane repair proteins revealed spatiotemporal cellular responses to plasma membrane damage

   Yuta Yamazaki, Keiko Kono
3. 1. Cell Biology

   Suppression of interferon signaling via small-molecule modulation of TFAM

   Dionisia Sideris, Husan Lee ... Lin Lyu

   Small-molecule mitochondrial transcription factor A modulators stabilize mtDNA, preventing cytosolic escape and suppressing cGAS-STING interferon signaling, while improving bioenergetics and fibrosis markers in disease models.
4. 1. Cell Biology

   A high-resolution, easy-to-build light-sheet microscope for subcellular imaging

   John Haug, Seweryn Gałecki ... Kevin M Dean

   An accessible light-sheet microscope delivers subcellular-resolution, multicolor volumetric, and live-cell imaging, lowering barriers to state-of-the-art performance.
5. 1. Cell Biology
   2. Neuroscience

   AutoMorphoTrack: A modular framework for quantitative analysis of organelle morphology, motility, and interactions at single-cell resolution

   Armin Bayati, Jackson G Schumacher, Xiqun Chen
6. 1. Cancer Biology
   2. Cell Biology

   Mitochondrial protein carboxyl-terminal alanine-threonine tailing promotes human glioblastoma growth by regulating mitochondrial function

   Bei Zhang, Ting Cai ... Zhihao Wu

   The carboxyl-terminal alanine-threonine-tailed protein ATP5α helps glioblastoma mitochondria maintain a high membrane potential and keep the permeability transition pore closed, thereby promoting tumor growth and increasing resistance to apoptosis.
7. 1. Cell Biology

   Specific GPCRs Elicit Unique Extracellular Vesicle MiRNA Array Signatures: An Exploratory Study

   Xiao Shi, Michelle C Palumbo ... Aaron Janowsky
8. 1. Cell Biology

   Axonal distribution of mitochondria maintains neuronal autophagy during aging via eIF2β

   Kanako Shinno, Yuri Miura ... Kanae Ando

   Upregulation of the β subunit of translation initiation factor eIF2 underlies autophagy suppression and premature aging caused by disruption of axonal transport of mitochondria.
9. 1. Cell Biology

   The IBEX knowledge-base a community resource enabling adoption and development of immunofluorescence imaging methods

   Ziv Yaniv, Ifeanyichukwu U Anidi ... Andrea J Radtke

   A dynamic, community-driven knowledge repository reduces research costs and accelerates scientific discovery by sharing validated reagent data, negative results, and protocols while rewarding contributors through formal authorship recognition.
10. 1. Cell Biology

    A single-cell atlas of the testicular interstitium defines Leydig progenitor networks sustaining Leydig cell homeostasis across the lifespan

    Xiaojia Huang, Kai Xia ... Wei Zhao

    Single-cell transcriptomic analysis of the murine testicular interstitium across the lifespan reveals Cd34⁺/Sox4⁺ mesenchymal cells as Leydig progenitors, whose aging-associated decline in glutathione and Sox4-regulated regenerative capacity inform potential therapeutic strategies for age-related testicular dysfunction.