Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Physiology

    Primary cilia in the growing limb are preferentially orientated, uncoupled from centriolar position

    Theana Johnson, Swati Midha ... Angus KT Wann
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Cell Biology

    Pre-rRNA represses gene transcription in the XY body of male germ cells

    Linlin Chen, Xiaochen Gai ... Xiaochun Yu
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Solid
    1. Cell Biology

    A GCN1-independent activator of the kinase GCN2

    JiaYi Zhu, Giulia Emanuelli ... Stefan J Marciniak
    GCN2 can be pharmacologically activated independently of GCN1, revealing flexibility in the mechanisms governing kinase activation.
    1. Cell Biology

    Small brown planthopper infestation enhances it reproduction and insecticide tolerance by manipulating glucose distribution and levels in rice

    Hainan Zhang, Qi Zhang ... Jianjun Wang
    Small brown planthopper infestation drives rice glucose redistribution to boost its own reproduction and insecticide tolerance.
    1. Cell Biology

    p66Shc mediates SUMO2-induced endothelial dysfunction

    Jitendra Kumar, Shravan K Uppulapu ... Santosh Kumar
    SUMO2ylation of redox protein p66Shc drives endothelial dysfunction by promoting oxidative stress, identifying a potential therapeutic target for cardiovascular disease.
    1. Cell Biology

    The microtubule-associated proteins CKAP2 and its paralog CKAP2-Like control ciliogenesis in human cells

    Luiz E da Silva, Gabriel Campolina-Silva ... Susanne Bechstedt
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete
    1. Cell Biology
    2. Genetics and Genomics

    Effects of knockdown of autophagy pathway genes on C. elegans longevity are highly condition dependent

    Kuei Ching Hsiung, Hannah Chapman ... David Gems
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Immunology and Inflammation

    Syntaxin11 deficiency inhibits CRAC channel priming to suppress cytotoxicity and gene expression in T lymphocytes independent of membrane trafficking

    Sritama Datta, Abhikarsh Gupta ... Monika Vig
    Syntaxin11 directly controls a novel step in the activation of calcium channels, which helps activate genes and kill infected cells by a process distinct from moving cargo inside cells.
    1. Cell Biology
    2. Developmental Biology

    Bruce suppresses autophagy-regulated caspase activity and wing tissue growth in Drosophila

    Natsuki Shinoda, Yutaro Hama ... Masayuki Miura
    The activity of Dcp-1, one of Drosophila executioner caspases, is selectively regulated by the autophagy–Bruce axis, which enables distinct non–lethal functions for promoting tissue growth independent of cell death.

Highlights

    1. Cell Biology
    Defeated wooden mannequin. Image credit: Marco Bianchetti (CC0)

    How to give cells an identity crisis

    Paige Dillon, Julie Hollien
    1. Cell Biology
    2. Developmental Biology
    Model of the heart. Image credit: Jesse Orrico (CC0)

    Following your heart as it takes shape

    Alexandra Trouilloud, Nicole C Dubois

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Felix Campelo
    Pompeu Fabra University, Spain
  3. Jonathan A Cooper
    Jonathan A Cooper
    Fred Hutchinson Cancer Research Center, United States
  4. See more editors