Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Genetics and Genomics

    Cytosolic Carboxypeptidase 5 maintains mammalian ependymal multicilia to ensure proper homeostasis and functions of the brain

    Rubina Dad, Yujuan Wang ... Hui-Yuan Wu
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Physics of Living Systems

    Sarcomere dynamic instability and stochastic heterogeneity drive robust cardiomyocyte contraction

    Daniel Haertter, Lara Hauke ... Christoph F Schmidt
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Compelling
    1. Cell Biology
    2. Genetics and Genomics

    Mechanistic insights into transcriptional regulation of ARHGAP36 expression identify a factor predictive of neuroblastoma survival

    Serhiy Havrylov, Armin M Gamper, Ordan J Lehmann
    Genetic experiments integrated with ChIP-sequencing and CRISPR interference reveal that overexpression of Foxc1 transcriptionally activates the expression of Arhgap36 and dysregulates multiple facets of Hedgehog pathway activity.
    1. Cell Biology
    2. Computational and Systems Biology

    Lipid packing contributes to the confinement of caveolae to the plasma membrane

    Elin Larsson, Aleksei Kabedev ... Richard Lundmark
    Membrane insertion of Dyngo-4a results in a dynamin-independent inhibition of caveola dynamics, revealing that outer leaflet lipid packing in the plasma membrane contributes to the confinement of caveolae.
    1. Cell Biology
    2. Neuroscience

    Activity-dependent CO2 production in the axon triggers opening of Connexin32 in the Schwann cell paranode

    Jack Butler, Lowell Mott ... Nicholas Dale
    Gaseous CO2 acts as a neuron to glia messenger in peripheral myelin to trigger opening of Schwann Cell Cx32 hemichannels in response to axonal action potential propagation.
    1. Cell Biology

    CROP2, a Retriever-PROPPIN Complex Mediating Protein Export from Endosomes to the Plasma Membrane

    Maria Giovanna De Leo, Andreas Mayer
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Non-canonical amino acid incorporation enables minimally disruptive labeling of stress granule and TDP-43 proteinopathy

    Hao Chen, Haocheng Wang ... Jiou Wang
    Minimally disruptive genetic code expansion enables faithful, site-specific labeling of G3BP1 and TDP-43, revealing native stress granule dynamics and ALS-linked protein behavior in live cells.
    1. Cell Biology

    Nuclear export modulates TDP-43 phase transition and cytoplasmic aggregation

    Natalie Chin, Qi Zhang ... Yihong Ye
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Cell Biology

    Wound-Induced Syncytia Outpace Mononucleate Neighbors during Drosophila Wound Repair

    James S White, Junmin Hua ... Andrea Page-McCaw
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology

    Membrane contact site resident PTP1B limits superoxide production by suppressing a Syk-Shc1-Phagocyte Oxidase relay

    Minhyoung Lee, Haggag S Zein ... Gregory D Fairn
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing

Highlights

    1. Cell Biology
    2. Neuroscience

    The role of lipids in hearing

    Yein Christina Park, Angela Ballesteros

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Felix Campelo
    Pompeu Fabra University, Spain
  3. David Ron
    Cambridge University, United Kingdom
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