Cell Biology

Latest articles

1. 1. Cell Biology

   ATG2A interacts with RAB1A and ARFGAP1 positive membranes during autophagosome biogenesis

   Devin M Fuller, Yumei Wu ... Thomas J Melia
2. 1. Cell Biology

   Polo-like kinase phosphorylation of the orphan kinesin KIN-G negatively regulates centrin arm biogenesis in Trypanosoma brucei

   Yasuhiro Kurasawa, Qing Zhou ... Ziyin Li

   Polo-like kinase phosphorylation of the centrin arm-localized orphan kinesin KIN-G disrupts its microtubule-binding activity and inhibits centrin arm biogenesis in trypanosomes.
3. 1. Cell Biology

   The insulin/IGF axis is critically important for controlling gene transcription in the podocyte

   Jenny A Hurcombe, Lusyan Dayalan ... Richard JM Coward

   Simultaneously knocking down both the insulin and IGF1 receptor in the kidney podocyte is highly detrimental, affecting spliceosome function and gene transcription.
4. 1. Cell Biology
   2. Structural Biology and Molecular Biophysics

   A biochemical mechanism for Stu2/XMAP215-family microtubule polymerases

   Binnu Gangadharan, Daniel L Kober, Luke M Rice

   Evolutionarily unrelated microtubule and actin regulatory factors use the same mechanism to accelerate polymerization.
5. 1. Cell Biology

   A high-throughput assay for the measurement of Ca²⁺-oscillations and insulin release from uniformly sized β-cell spheroids

   Stijn Robben, Patricia Davidson ... Thomas Voets
6. 1. Cell Biology

   Cardiolipin deficiency disrupts electron transport chain and drives steatohepatitis

   Marisa J Brothwell, Guoshen Cao ... Katsuhiko Funai

   Metabolic dysfunction-associated steatotic liver disease is associated with reduced mitochondrial cardiolipin concentration in mice and humans, and cardiolipin deficiency was sufficient to drive steatosis and fibrosis in the liver.
7. 1. Cell Biology

   Xkr regulates phosphatidylserine transport via ER-PM contact sites to promote apoptotic cell clearance

   Qian Zheng, Xinyu Ma ... Hui Xiao
8. 1. Cell Biology

   MARBL: A Live-Cell Method for Profiling Bioenergetic Heterogeneity by Noncanonical Methionine Labeling of the Cell Surface Proteome

   Lillian R Delacruz, Ming Ye ... Alison E Ringel
9. 1. Cell Biology

   Functional High Throughput Drug Screening Reveals Cyproheptadine as a Novel Treatment for LMNA-related Cardiomyopathy

   Hananeh Fonoudi, Ali Negahi Shirazi ... Paul W Burridge
10. 1. Cell Biology
    2. Neuroscience

    Tau hyperphosphorylation impairs cooperative binding to microtubules and perturbs organelle trafficking in neurons

    Daniel Beaudet, Christopher L Berger, Adam G Hendricks