Cell Biology

Latest articles

1. 1. Cell Biology

   Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism

   Fangqing Deng, Rong Yang ... Lianbing Zhang

   Periodic red-light irradiation promotes coupling between keratinocyte mitochondrial lipid metabolism and epigenetic remodeling, increasing acetyl-CoA availability and histone H3 lysine 9 acetylation to slow skin aging.
2. 1. Cell Biology

   Golgi CATCHR complexes function as organizing hubs for vesicle tethering and fusion

   Walter S Aragon-Ramirez, Amrita Khakurel ... Vladimir V Lupashin
3. 1. Cell Biology
   2. Microbiology and Infectious Disease

   Tracking maternal proteins uncovers a central role for the residual body in organelle recycling during Toxoplasma gondii replication

   Julia von Knoerzer-Suckow, Parnian Sazegar ... Markus Meissner
4. 1. Cell Biology

   A high-throughput assay for the measurement of Ca²⁺ oscillations and insulin release from uniformly sized mouse β-cell (MIN6) spheroids

   Stijn Robben, Patricia Davidson ... Thomas Voets

   High-throughput monitoring of glucose-evoked calcium oscillations in uniform 3D β-cell spheroids enables efficient discovery of compounds that enhance insulin secretion.
5. 1. Cell Biology
   2. Developmental Biology

   Zinc is a key regulator of the sperm-specific K⁺ channel (Slo3) function

   Rizki Tsari Andriani, Tanadet Pipatpolkai ... Takafumi Kawai

   Intracellular zinc dynamically changes during sperm capacitation and regulates Slo3-mediated hyperpolarization, while directly inhibiting Slo3 currents through residues contributing to its slow dissociation.
6. 1. Cell Biology
   2. Neuroscience

   Tau hyperphosphorylation impairs cooperative binding to microtubules and perturbs organelle trafficking in neurons

   Daniel Beaudet, Christopher L Berger, Adam G Hendricks

   Single-molecule motility assays and live-cell imaging in neurons reveal that tau hyperphosphorylation disrupts the formation of cooperative tau envelopes along microtubules and lysosomal transport.
7. 1. Cell Biology
   2. Immunology and Inflammation

   Digest before Ingest: Early Recruitment of Membrane-bound DNaseX to Phagocytic Cups in Macrophages

   Arghajit Pyne, Vivek Pandey ... Xuefeng Wang
8. 1. Cell Biology
   2. Physiology

   Ion channels and GPCR requirements for pressure-induced lymphatic chronotropy: Evidence for a Gα_q/11-IP₃R1-ANO1 pacemaking axis

   Michael J Davis, Hae Jin Kim ... Scott D Zawieja
9. 1. Cell Biology
   2. Genetics and Genomics

   Effects of knockdown of autophagy pathway genes on C. elegans longevity are highly condition dependent

   Kuei Ching Hsiung, Hannah Chapman ... David Gems
10. 1. Cell Biology

    A Quartet of Native Orai Channel Isoforms Orchestrates Graded NFAT Activation and Transcription

    Ahmed Emam Abdelnaby, Yin-Hu Wang ... Mohamed Trebak