Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology

    Disruption of sphingolipid metabolism promotes tau seeding through endolysosomal membrane rigidification and rupture

    Jessica Tittelmeier, Carl Alexander Sandhof ... Carmen Nussbaum-Krammer
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology

    Defective Neuronal Differentiation in Lowe Syndrome is Associated with Mitochondrial Dysfunction and Impaired Cilia-related Sonic Hedgehog Signaling

    Grzegorz Walkiewicz, Siyu Chen ... Yang Sun
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    A tool to pulse-label yeast Nuclear Pore Complexes in imaging and biochemical experiments

    Annemiek C Veldsink, Jonas S Fischer ... Liesbeth M Veenhoff
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Physiology

    Aging induced structural alterations in SR-Mitochondria interaction in skeletal muscle: Emerging insights

    Unmod Senapati, Barsha Priyadarshini Kar ... Naresh Chandra Bal
    Not revised
    Reviewed Preprint v1
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Enteropathogenic Escherichia coli-mediated fast and coordinated Ca²+ responses regulate NF-κB activation

    Fangrui Guo, Roberto Ornelas Guevara ... Guy Tran Van Nhieu
    Through low levels of extracellular ATP, EPEC induces small, rapid and coordinated Ca2+ responses in epithelial cells, a yet unreported pattern, that down-regulate inflammation at the onset of infection.
    1. Cell Biology

    Opto-MDMi: a dual-lock optogenetic system for robust activation of endogenous p53

    Tatsuki Tsuruoka, Takashi Sumikama ... Kazuhiro Aoki
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Cancer Biology
    2. Cell Biology

    DuoHexaBody-CD37 induces direct cytotoxic signaling in diffuse large B-cell lymphoma

    Simar Pal Singh, Kumar Mangalam ... Annemiek B van Spriel
    DuoHexaBody‑CD37 triggers complement‑independent cytotoxic signaling in diffuse large B-cell lymphoma (DLBCL), revealing therapeutic pathways that can be exploited to enhance tumor cell killing through targeted combination strategies.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    DNA tensiometer reveals catch-bond detachment kinetics of kinesin-1, -2, and -3

    Crystal R Noell, Tzu-Chen Ma ... William O Hancock
    All three kinesin transport families exhibit unexpectedly slow dissociation under load, explaining robust competition with dynein during bidirectional cargo transport.
    1. Cell Biology
    2. Neuroscience

    FMRP regulates neuronal RNA granules containing stalled ribosomes, not where ribosomes stall

    Jewel T-Y Li, Mehdi Amiri ... Wayne S Sossin
    The loss of FMRP does not affect how neuronal ribosomes are stalled or where they are stalled, but reduces the number of neuronal RNA granules that contain stalled ribosomes.

Highlights

    1. Cell Biology
    2. Neuroscience

    The role of lipids in hearing

    Yein Christina Park, Angela Ballesteros

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Felix Campelo
    Pompeu Fabra University, Spain
  3. Jonathan A Cooper
    Jonathan A Cooper
    Fred Hutchinson Cancer Research Center, United States
  4. See more editors