Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Immunology and Inflammation

    Allosteric disulfide control of ligand binding and endocytosis of KIR2DL4, the natural killer cell receptor for HLA-G

    Sumati Rajagopalan, Joyce Chiu ... Eric O Long
    Allosteric transition between two disulfide configurations of NK cell receptor KIR2DL4 is a functional switch that controls receptor residence at the cell surface for binding and internalization of soluble HLA-G.
    1. Cell Biology
    2. Neuroscience

    Endosome-associated Rab GTPases control distinct aspects of neural circuit assembly

    Katherine X Dong, Yanbo Zhang ... Colleen N McLaughlin
    Systematic dissection of Rab GTPase function in developing neurons reveals that early and recycling endosome-associated Rabs regulate largely distinct aspects of neuronal morphogenesis and circuit assembly across developmental time.
    1. Cell Biology

    Whole human organ clearing and multimodal mapping

    Héloïse Policet-Bétend, Tomàs Jordà-Siquier ... Christophe M Lamy
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Cell Biology
    2. Cancer Biology

    P95-HER2 promotes metastatic progression by biasing MRTFA dependent signaling

    Joseph D Fernandes, Erin Bresnahan ... Joshua C Snyder
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology
    2. Neuroscience

    A validated antibody toolbox for ALS research

    Riham Ayoubi, Emma J MacDougall ... Carl Laflamme
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Cell Biology
    2. Developmental Biology

    Krüppel Regulates Cell Cycle Exit and Limits Adult Neurogenesis of Mushroom Body Neural Progenitors in Drosophila

    Dongni Shao Chen, Jin Man ... Yuu Kimata
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Cell Biology

    Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism

    Fangqing Deng, Rong Yang ... Lianbing Zhang
    Periodic red-light irradiation promotes coupling between keratinocyte mitochondrial lipid metabolism and epigenetic remodeling, increasing acetyl-CoA availability and histone H3 lysine 9 acetylation to slow skin aging.
    1. Cell Biology

    Early recruitment of membrane-bound DNaseX to phagocytic cups in macrophages

    Arghajit Pyne, Vivek Pandey ... Xuefeng Wang
    Phagocytic cups of macrophages exhibit strong DNase activity during the early stage of phagocytosis, prior to cup closure.
    1. Cell Biology

    Golgi CATCHR complexes function as organizing hubs for vesicle tethering and fusion

    Walter S Aragon-Ramirez, Amrita Khakurel ... Vladimir V Lupashin
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Tracking maternal proteins uncovers a central role for the residual body in organelle recycling during Toxoplasma gondii replication

    Julia von Knoerzer-Suckow, Parnian Sazegar ... Markus Meissner
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
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Highlights

    1. Cell Biology
    2. Computational and Systems Biology
    Image credit: vividbiology.com

    The power of theory in the life sciences

    Jacob L Fine, Finn Creeggan ... Adam MR Groh
    1. Cell Biology
    Defeated wooden mannequin. Image credit: Marco Bianchetti (CC0)

    How to give cells an identity crisis

    Paige Dillon, Julie Hollien
    1. Cell Biology
    2. Developmental Biology
    Model of the heart. Image credit: Jesse Orrico (CC0)

    Following your heart as it takes shape

    Alexandra Trouilloud, Nicole C Dubois

Senior editors

  1. Felix Campelo
    Pompeu Fabra University, Spain
  2. Lynne-Marie Postovit
    University of Alberta, Canada
  3. Dominique Soldati-Favre
    University of Geneva, Switzerland
  4. See more editors