Cell Biology

Latest articles

1. 1. Cell Biology

   Nim1-related kinases regulate septin organization and cytokinesis by modulating Hof1 at the cell division site

   Bindu Bhojappa, Anubhav Dhar ... Saravanan Palani

   Septin-associated kinases functions in an adaptable regulatory network with overlapping functions to coordinate septin organization with actomyosin ring machinery to ensure robust cytokinesis in Saccharomyces cerevisiae.
2. 1. Cell Biology

   Wound-Induced Syncytia Outpace Mononucleate Neighbors during Drosophila Wound Repair

   James S White, Junmin Hua ... Andrea Page-McCaw
3. 1. Cell Biology

   Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism

   Fangqing Deng, Rong Yang ... Lianbing Zhang
4. 1. Cancer Biology
   2. Cell Biology

   Slap restricts oncogenic Src-family kinase signaling to maintain colonic epithelial homeostasis

   Dana Naim, Zouheir Houhou ... Serge Roche

   Src-like adaptor protein (SLAP) preserves intestinal epithelial homeostasis by restraining Src-family kinase signaling, revealing a non-genetic mechanism limiting colorectal tumor initiation.
5. 1. Cell Biology

   Cellular modifiers of TDP-43 phase transition and cytoplasmic aggregation

   Natalie Chin, Qi Zhang ... Yihong Ye

   A genome-wide RNA interference screen identified cellular processes that modulate the phase separation of a TDP-43 mutant, providing a framework for dissecting the link between its phase behavior and disease-associated aggregation.
6. 1. Cell Biology
   2. Neuroscience

   BetaII-spectrin gaps and patches emerge from the patterned assembly of the actin/spectrin membrane skeleton in human motor neuron axons

   Nahir Guadalupe Gazal, Maria Jose Castellanos-Montiel ... Nicolás Unsain

   An actin-nucleation-dependent assembly of the axonal membrane skeleton reveals that βII-spectrin gap-and-patch patterns in human motor neurons represent an intermediate stage of cytoskeletal maturation.
7. 1. Cell Biology

   Centrosome migration and apical membrane formation during epithelial polarization in MDCK cysts

   Po-Kai Wang, Keng-Hui Lin, Tang K Tang

   Single-cell observations refute the expectation that centrosome positioning is critical for epithelial cell polarization while showing that proper positioning enhances polarization efficiency.
8. 1. Cell Biology

   Synergistic effects of deleting the tyrosine phosphatases Shp1 and Shp2 on megakaryopoiesis and thrombopoiesis in mice

   Elsa Barré, Marc-Damien Lourenco-Rodrigues ... Alexandra Mazharian
9. 1. Cell Biology

   ATG2A interacts with RAB1A and ARFGAP1 positive membranes during autophagosome biogenesis

   Devin M Fuller, Yumei Wu ... Thomas J Melia
10. 1. Cell Biology

    Polo-like kinase phosphorylation of the orphan kinesin KIN-G negatively regulates centrin arm biogenesis in Trypanosoma brucei

    Yasuhiro Kurasawa, Qing Zhou ... Ziyin Li

    Polo-like kinase phosphorylation of the centrin arm-localized orphan kinesin KIN-G disrupts its microtubule-binding activity and inhibits centrin arm biogenesis in trypanosomes.