Cell Biology

Latest articles

1. 1. Cell Biology

   A Quartet of Native Orai Channel Isoforms Orchestrates Graded NFAT Activation and Transcription

   Ahmed Emam Abdelnaby, Yin-Hu Wang ... Mohamed Trebak
2. 1. Cell Biology
   2. Cancer Biology

   Molecular and Functional Analysis of Calcium Binding by a Cancer-linked Calreticulin Mutant

   Ishmael Nii Ayibontey Tagoe, Amanpreet Kaur ... Malini Raghavan
3. 1. Cell Biology

   Wound-induced syncytia outpace mononucleate neighbors during Drosophila wound repair

   James S White, Junmin Hua ... Andrea Page-McCaw

   In vivo live imaging, quantitative analysis, and computational modeling reveal that wound-induced epithelial cell fusion accelerates epithelial repair through several likely mechanisms.
4. 1. Cell Biology

   Winding-Up of Fibrin Fibers as a Novel Mechanism of Platelet-Mediated Fiber Compaction

   Alexei Grichine, Tatiana Kovalenko ... Karin Sadoul
5. 1. Cell Biology
   2. Neuroscience

   Endosome-associated Rab GTPases control distinct aspects of neural circuit assembly

   Katie X Dong, Yanbo Zhang ... Colleen N McLaughlin
6. 1. Cell Biology

   Defective neuronal differentiation in Lowe syndrome is associated with mitochondrial dysfunction and impaired cilia-related Sonic Hedgehog signaling

   Grzegorz Walkiewicz, Siyu Chen ... Yang Sun

   OCRL deficiency is associated with mitochondrial dysfunction, altered ciliary signaling, and disrupted neural cell-state regulation across multiple experimental models of Lowe syndrome.
7. 1. Cell Biology
   2. Computational and Systems Biology

   Philosophy of Biology: The power of theory in the life sciences

   Jacob L Fine, Finn Creeggan ... Adam MR Groh

   Theory can help address cell and molecular biology’s major challenges, particularly those arising from large omics datasets.
8. 1. Cell Biology

   Syntaxin11 Deficiency Inhibits CRAC Channel Priming to Suppress Cytotoxicity and Gene Expression in T Lymphocytes Independent of Membrane Trafficking

   Sritama Datta, Abhikarsh Gupta ... Monika Vig
9. 1. Cell Biology
   2. Neuroscience

   TRPML1 positions lysosomes and regulates actin-membrane linkers in astrocyte processes

   Maeve L Spivey, Madison L Fuller ... Sandra Maday
10. 1. Cell Biology
    2. Physics of Living Systems

    Sarcomere dynamic instability and stochastic heterogeneity drive robust cardiomyocyte contraction

    Daniel Haertter, Lara Hauke ... Christoph F Schmidt

    A non-monotonic force–velocity relationship in cardiac sarcomeres causes dynamic instability, leading to stochastic heterogeneity in contracting cardiomyocytes, which can have a protective function.