Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
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Latest articles

    1. Cell Biology
    2. Microbiology and Infectious Disease

    Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with nuclear speckles

    Chiara Tomasini, Celine Cuche ... Francesca Di Nunzio
    HIV hijacks SRRM2 to enlarge nuclear speckles, stabilizing CPSF6 puncta and promoting efficient viral replication.
    1. Cell Biology

    A conserved Hsp70 phosphorylation regulates cell cycle progression after DNA damage

    Thomas Moss, Alexandra Wooldredge ... Shaeri Mukherjee
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology

    A Novel 3D Visualization Method in Mice Identifies the Periportal Lamellar Complex (PLC) as a Key Regulator of Hepatic Ductal and Neuronal Branching Morphogenesis

    Tongtong Xu, Fujun Cao ... Chengjian Zhao
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    • Incomplete
    1. Cell Biology

    Efficiency and localisation of AURKA degradation by PROTACs is modulated by deubiquitinases UCHL5 and target-selective OTUD6A

    Annabel Cardno, Karen Roberts, Catherine Lindon
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology

    The IBEX Knowledge-Base: A Community Resource Enabling Adoption and Development of Immunofluorescence Imaging Methods

    Ziv Yaniv, Ifeanyichukwu U Anidi ... Andrea J Radtke
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Exceptional
    1. Cell Biology

    CCDC32 stabilizes clathrin-coated pits and drives their invagination

    Ziyan Yang, Changsong Yang ... Zhiming Chen
    Live cell imaging and biochemical analyses reveal that CCDC32 interacts with AP2 to stabilize and drive invagination of clathrin-coated pits, and that clinical mutations disrupting this interaction cause cardio-facio-neuro-developmental syndrome.
    1. Cell Biology
    2. Immunology and Inflammation

    Male-Biased Cyp17a2 Orchestrates Antiviral Sexual Dimorphism in Fish via STING Stabilization and Viral Protein Degradation

    Long-Feng Lu, Bao-jie Cui ... Shun Li
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Cell Biology

    Specific proteolysis mediated by a p97-directed proteolysis-targeting chimera (p97-PROTAC)

    Constanza Salinas-Rebolledo, Javier Blesa ... Alejandro Rojas-Fernandez
    Synthetic adaptors combining camelid nanobodies with the UBX domain of the p97 adaptor FAF1 enable targeted substrate delivery to p97, establishing an E3 ubiquitin ligase-independent mechanism for selective protein degradation.
    1. Cell Biology

    JAK-STAT pathway activation compromises nephrocyte function in a Drosophila high-fat diet model of chronic kidney disease

    Yunpo Zhao, Jianli Duan ... Zhe Han
    A conserved signaling axis linking Drosophila adipose tissue to nephrocyte function reveals how obesity can drive kidney dysfunction and points to new opportunities for therapeutic intervention.
    1. Cell Biology

    Altair-LSFM: A High-Resolution, Easy-to-Build Light-Sheet Microscope for Sub-Cellular Imaging

    John Haug, Seweryn Gałecki ... Kevin M Dean
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
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Highlights

    1. Structural Biology and Molecular Biophysics
    2. Cell Biology
    3. Biochemistry and Chemical Biology

    Allosteric Regulation of Kinase Activity – call for papers

    1. Cell Biology
    2. Developmental Biology

    Imaging methods are vastly underreported

    Guillermo Marqués, Thomas Pengo, Mark A Sanders
    1. Cell Biology
    2. Developmental Biology

    Philosophy of Biology: Knowledge and illusions

    Antony M Jose

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Felix Campelo
    Pompeu Fabra University, Spain
  3. Dominique Soldati-Favre
    University of Geneva, Switzerland
  4. See more editors