Cell Biology

Latest articles

1. 1. Cell Biology
   2. Genetics and Genomics

   Cross-species evaluation of TANGO2 homologs, including HRG-9 and HRG-10 in Caenorhabditis elegans, challenges a proposed role in heme trafficking

   Sarah E Sandkuhler, Kayla S Youngs ... Samuel J Mackenzie

   Evidence from multiple model systems supports a shift away from heme transport and toward metabolic dysfunction and oxidative stress as key drivers of TANGO2 deficiency.
2. 1. Cell Biology

   Centrosome Migration and Apical Membrane Formation in Polarized Epithelial Cells: Insights from the MDCK Cyst Model

   Po-Kai Wang, Keng-Hui Lin, Tang K Tang
3. 1. Cell Biology
   2. Microbiology and Infectious Disease

   Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with nuclear speckles

   Chiara Tomasini, Celine Cuche ... Francesca Di Nunzio

   HIV hijacks SRRM2 to enlarge nuclear speckles, stabilizing CPSF6 puncta and promoting efficient viral replication.
4. 1. Cell Biology

   A Novel 3D Visualization Method in Mice Identifies the Periportal Lamellar Complex (PLC) as a Key Regulator of Hepatic Ductal and Neuronal Branching Morphogenesis

   Tongtong Xu, Fujun Cao ... Chengjian Zhao
5. 1. Cell Biology

   A conserved Hsp70 phosphorylation regulates cell cycle progression after DNA damage

   Thomas Moss, Alexandra Wooldredge ... Shaeri Mukherjee
6. 1. Cell Biology

   Efficiency and localisation of AURKA degradation by PROTACs is modulated by deubiquitinases UCHL5 and target-selective OTUD6A

   Annabel Cardno, Karen Roberts, Catherine Lindon
7. 1. Cell Biology

   The IBEX Knowledge-Base: A Community Resource Enabling Adoption and Development of Immunofluorescence Imaging Methods

   Ziv Yaniv, Ifeanyichukwu U Anidi ... Andrea J Radtke
8. 1. Cell Biology

   CCDC32 stabilizes clathrin-coated pits and drives their invagination

   Ziyan Yang, Changsong Yang ... Zhiming Chen

   Live cell imaging and biochemical analyses reveal that CCDC32 interacts with AP2 to stabilize and drive invagination of clathrin-coated pits, and that clinical mutations disrupting this interaction cause cardio-facio-neuro-developmental syndrome.
9. 1. Cell Biology
   2. Immunology and Inflammation

   Male-Biased Cyp17a2 Orchestrates Antiviral Sexual Dimorphism in Fish via STING Stabilization and Viral Protein Degradation

   Long-Feng Lu, Bao-jie Cui ... Shun Li
10. 1. Cell Biology

    Specific proteolysis mediated by a p97-directed proteolysis-targeting chimera (p97-PROTAC)

    Constanza Salinas-Rebolledo, Javier Blesa ... Alejandro Rojas-Fernandez

    Synthetic adaptors combining camelid nanobodies with the UBX domain of the p97 adaptor FAF1 enable targeted substrate delivery to p97, establishing an E3 ubiquitin ligase-independent mechanism for selective protein degradation.