Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Medicine

    The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence

    Fan Zhang, Yuan Wang ... Xianpeng Ge
    CHMP5 is crucial in preventing skeletal progenitor cell senescence and abnormal bone formation, and senolytic drugs represent potential therapeutic medicine for musculoskeletal abnormalities associated with a dysfunctional endolysosomal pathway.
    1. Cell Biology

    The molecular logic of Gtr1/2- and Pib2-dependent TORC1 regulation in budding yeast

    Jacob H Cecil, Cristina M Padilla ... Andrew P Capaldi
    Dual regulation of TORC1 by Gtr1/2 and Pib2 drives cells into three distinct signaling states, establishing a new paradigm for graded TORC1 signaling.
    1. Cell Biology
    2. Developmental Biology

    Female-germline specific protein Sakura interacts with Otu and is crucial for germline stem cell renewal and differentiation and oogenesis

    Azali Azlan, Li Zhu, Ryuya Fukunaga
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Neuroscience

    Endophilin A1 facilitates organization of the GABAergic postsynaptic machinery to maintain excitation-inhibition balance

    Xue Chen, Deng Pan ... Yanrui Yang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology

    Negative regulation of miRNA sorting into EVs is mediated by the capacity of RBP PCBP2 to impair the SYNCRIP-dependent miRNA loading

    Francesco Marocco, Sabrina Garbo ... Marco Tripodi
    PCBP2 promotes miRNA cell retention by counteracting SYNCRIP-dependent miRNAs EV loading.
    1. Cell Biology
    2. Developmental Biology

    Planar cell polarity coordination in a cnidarian embryo provides clues to animal body axis evolution

    Julie Uveira, Antoine Donati ... Tsuyoshi Momose
    The jellyfish embryonic body axis is globally coordinated by conserved planar cell polarity (PCP) mechanisms and oriented by localised Wnt3 in two steps, highlighting PCP’s role in animal axis evolution.
    1. Cell Biology

    Engineered Migrasomes: Harnessing Core Migrasome Machinery and Hypotonic Shock to Develop a Robust and Thermally Stable Vaccine Platform

    Dongju Wang, Haifang Wang ... Zhihua Liu
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Cell Biology

    Cellular characterization of the mouse collecting lymphatic vessels reveals that lymphatic muscle cells are the innate pacemaker cells

    Scott D Zawieja, Grace A Pea ... Michael J Davis
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Convincing
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Functionally-Coupled Ion Channels Begin Co-assembling at the Start of Their Synthesis

    Roya Pournejati, Jessica M Huang ... Oscar Vivas
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cell Biology

    FMRP Regulates Neuronal RNA Granules Containing Stalled Ribosomes, Not Where Ribosomes Stall

    Jewel T-Y Li, Mehdi Amiri ... Wayne S Sossin
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
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Highlights

    1. Structural Biology and Molecular Biophysics
    2. Cell Biology
    3. Biochemistry and Chemical Biology

    Allosteric Regulation of Kinase Activity – call for papers

    1. Cell Biology
    2. Developmental Biology

    Imaging methods are vastly underreported

    Guillermo Marqués, Thomas Pengo, Mark A Sanders
    1. Cell Biology
    2. Developmental Biology

    Philosophy of Biology: Knowledge and illusions

    Antony M Jose

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Felix Campelo
    Pompeu Fabra University, Spain
  3. Richard M White
    Ludwig Institute for Cancer Research, University of Oxford, United Kingdom
  4. See more editors