Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Michele Marconcini, Steeve Cruchet ... Richard Benton
Selection of animal populations and of cultured cells provides complementary datasets to identify candidate genes involved in conferring resistance to a natural insecticide.
Revealing a role for NINJ2 in maintaining lysosomal homeostasis and preventing ferroptosis, laying the foundation for the development of cancer therapeutics targeting NINJ2.
Rémi Pichon, Magda E Lotkowska ... Gabriel Rinaldi
Establishment of sexually dimorphic schistosomes entirely in vitro from mechanically transformed cercariae paves the way for uncovering the cellular and molecular cues underlying development, providing potential targets for novel control strategies.
Repeat variation in wild Arabidopsis thaliana arises from centromere-proximal sequence changes and rare variants in DNA replication, repair, and methylation genes, consistent with purifying selection constraining genome expansion.
Septin-associated kinases functions in an adaptable regulatory network with overlapping functions to coordinate septin organization with actomyosin ring machinery to ensure robust cytokinesis in Saccharomyces cerevisiae.
Anne R Van Arsdale, Olga Meshcheryakova ... Jack Lenz
HPV-human DNA junction detection in serum cell-free DNA unambiguously identifies tumor genetic-signatures of integrated viral DNA from HPV-induced cancers and could be useful for recurrence prediction and monitoring residual disease.
At moderate densities, small mammalian herbivores can enhance livestock weight gains by suppressing toxic plants and improving both the abundance and nutritional quality of palatable forage in rangelands.
Primordial cardiomyocytes play an essential role in myocardial morphogenesis and coronary vascularization, but not in adult zebrafish heart regeneration.
A genome-wide RNA interference screen identified cellular processes that modulate the phase separation of a TDP-43 mutant, providing a framework for dissecting the link between its phase behavior and disease-associated aggregation.
