Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Rachel H Clare, Adam Westhorpe ... Nicholas R Casewell
Despite the variation in venom across the Bothrops snake genus, repurposed drugs demonstrated pan-species neutralisation in enzymatic, coagulation, and haemorrhage assays, highlighting their value as novel therapies for Neotropical snakebites.
Fangfang Hong, Ruby Bouhassira ... David H Brainard
Leveraging the smooth variation of internal noise makes comprehensive characterization of color discrimination practical, offering an efficient framework for studying perceptual limits across various sensory domains.
Inflammatory activation of endothelial cells triggers Pink1-dependent mitophagy and mitochondrial formyl peptides release, which drives neutrophil recruitment and lung injury.
Fundamental distinctions in the extracellular signatures of active-dendritic chemical and electrical synapses necessitate a revision of conventional interpretations of local field potentials centered on chemical synapses.
A time-dependent genetic interaction between the µ opioid receptor and genes drives early morphine responses in mice, highlighting pathways linked to human substance use disorder.
Gaze patterns during value-based choice may reflect post-decision processes rather than a direct causal influence of attention on preference formation.
Kely Catarine Matteucci, Nathalia PS Leite ... Ricardo T Gazzinelli
TNF-driven metabolic reprogramming enhances glucose utilization in monocytes through inducible nitric oxide synthase (iNOS) and hypoxia-inducible factor 1α (HIF-1α), promoting parasite control and host resistance during Plasmodium infection.