Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Vikram Chandra, Samantha Elizabeth Tseng ... Mansi Srivastava
Studying the reproductive life history of an acoel reveals that a body-size-dependent program regulates organ growth and regeneration dynamics and discovers a novel form of egg-laying behavior.
Inactivation of beta 1,4-galactosyltransferase 1 leads to enhanced T-cell receptor activation and CD8+ T-cell function by affecting the galactosylation of T-cell receptor and CD8.
Unique extracellular vesicle microRNA signatures resulting from G protein-coupled receptor activation indicate distinct downstream signaling and functional networks by receptor, with implications for developing new drugs and understanding their long-term and off-target effects.
Profiling endogenous Bruchpilot proteins in multiple cell types in mushroom bodies uncovered multilayered spatial configurations of active zones, from stereotyped intracellular distribution patterns to local arrangements of neighboring synapses.
At birth, infant visual cortex connectivity resembles that of blind adults, while lifetime visual experience enhances long-range functional connectivity between visual cortices, sensorimotor systems, and dampens connectivity with executive networks.
Functional connectivity reveals brain attractors that match predictions of free‑energy‑minimizing attractor theory, yielding an interpretable generative model of brain dynamics in rest, task, and disease.
Mycobacterium tuberculosis utilizes nucleomodulins to disrupt host inflammatory responses and lysosomal maturation, uncovering a novel strategy for immune evasion and intracellular survival.
