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    1. Biochemistry and Chemical Biology

    New SARS-CoV-2 target could boost immunity against all coronaviruses

    Researchers have identified a conserved region of the SARS-CoV-2 spike protein that could be targeted to boost human antibody responses against any coronavirus.
  1. Media Coverage: February roundup of eLife papers in the news

    High-profile news coverage that eLife papers generated in February 2023, including The Scientist, The ASCO Post and Earth.com.
    1. Microbiology and Infectious Disease

    How malaria parasite prioritises growth or transmission

    Plasmodium falciparum, a parasite species highly associated with malaria, can rapidly respond to changes in its host environment by investing into replication or transmission.
    1. Genetics and Genomics
    2. Neuroscience

    How fruit flies feast for pleasure as well as necessity

    A study suggests that fruit flies experience two hunger states – one driven by need and the other by pleasure – which arise from unique neural mechanisms.
    1. Cancer Biology

    Scientists discover new lead in hunt for myeloma drug

    Researchers have shown that a fatty acid binding protein is a key target linked to more aggressive disease and poorer survival in multiple myeloma.
    1. Epidemiology and Global Health

    Localised lockdowns could control pandemics while reducing socio-economic impact

    Researchers have built a model to predict how local tailoring of pandemic control measures such as lockdowns can halt disease transmission while reducing societal burden.
    1. Epidemiology and Global Health

    How differences in individual infections affect COVID-19 spread within households

    A subset of individuals with SARS-CoV-2 are three times more likely to spread the virus to other individuals than the average person.
    1. Medicine

    Less than one in ten Phase III clinical trials are ever cited at the point-of-care

    A decade-long analysis reveals potential bottlenecks in the pathway of clinical research into medical practice.
    1. Medicine

    Study supports evidence ivermectin is ineffective at treating COVID-19

    PLATCOV, a platform to assess the effectiveness of drugs against COVID-19, suggests that ivermectin has no significant antiviral activity against SARS-CoV-2.
    1. Evolutionary Biology

    Multiple mutations may help Omicron variant escape antibodies

    Just one or two mutations with strong effects, or an accumulation of mutations with small effects, may help the Omicron variant of SARS-CoV-2 dodge the immune system or antibody-based therapies.