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Complementary structural biology approaches reveal how an agonist and a covalent inhibitor simultaneously bind to a nuclear receptor.

There is an ongoing need for researchers and all stakeholders to better understand issues surrounding antibody characterization to improve the quality and reproducibility of research that employs these reagents.

A neural signature of serial dependence has been found, which mirrors the attractive bias of visual information seen in behavioral experiments.

By altering which peptide antigens are presented to CD4⁺ T cells, adjuvants affect the specificity of the immune response.

Body movement does not significantly increase neuronal activity in the primary visual cortex of marmosets, in contrast to the effects observed in mice.

A postdoc explains how being medicated for bipolar changed her life and the way she conducts research.

Establishing a zebrafish model of a deadly type of brain tumor highlights the role of the immune system in the early stages of the disease.

Abnormal activity in the cerebellar nuclei can be used to predict motor symptoms and induce them experimentally, pointing to potential therapeutic strategies.

When deciding which submissions should be peer reviewed, eLife editors consider whether they will be able to find high-quality reviewers, and whether the reviews will be valuable to the scientific community.

A new mathematical model can estimate the number of precursor cells that contribute to regenerating blood cells in mice.