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    1. Structural Biology and Molecular Biophysics

    Ion Channels: Poring over furrows

    Skylar ID Fisher, H Criss Hartzell
    Cryo-electron microscopy reveals the structure of a chloride channel that is closely related to a protein that transports lipids.
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    1. Neuroscience

    Thermoregulation: How a brain keeps its cool

    Swathi Yadlapalli, Orie T Shafer
    Temperature-sensing neurons in the Drosophila brain cooperate with the central circadian clock to help regulate body temperature.
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  3. Editor’s choice: an interview with Yaiza del Pozo Martín

    When she realised that reading papers and discussing science was just as enjoyable as doing research, Yaiza del Pozo Martín decided to move away from a career as a postdoc to try something different. She now works as an Assistant Editor for BMJ Open.
    1. Neuroscience

    Axons: The cost of communication in the brain

    Brian A MacVicar, Leigh Wicki-Stordeur, Louis-Philippe Bernier
    Imaging ATP in axons reveals that they rely on glucose from the blood and lactate produced by glial cells as sources of energy.
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    1. Developmental Biology

    Evolutionary Developmental Biology: Sensing oxygen inside and out

    Maria R Stupnikov, Wellington V Cardoso
    Neuroendocrine cells act as oxygen sensors in animals from fish to humans, but the evolutionary origins of these cells are only just becoming clear.
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    1. Evolutionary Biology

    Population Genetics: Global clues to the nature of genomic mutations in humans

    Aylwyn Scally
    An analysis of worldwide human genetic variation reveals the footprints of ancient changes in genomic mutation processes.
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    1. Neuroscience

    Chemoreception: Keeping carbon dioxide in check

    Alfredo J Garcia III, Jan-Marino Ramirez
    The response of the brainstem to increased levels of carbon dioxide in the blood is coordinated with the response of the cardiovascular system.
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    1. Structural Biology and Molecular Biophysics
    2. Immunology and Inflammation

    Cell Signaling: Extraordinary effects of unnatural pairings

    Alejandro Villarino, John J O'Shea
    Engineered molecules based on human cytokines have potential uses in research and medicine.
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    1. Developmental Biology
    2. Evolutionary Biology

    Multicellularity: The evolution of gene regulation

    Veronica Hinman, Gregory Cary
    The gene regulation mechanisms necessary for the development of complex multicellular animals have been found in sponges.
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    1. Evolutionary Biology

    Human Evolution: New opportunities rising

    Jessica C Thompson
    More fossil specimens and an eagerly awaited age for Homo naledi raise new questions and open new opportunities for paleoanthropologists.
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