A curated resource to study the brain RNA expression patterns of the genes that regulate palmitoylation is presented, alongside a detailed exploration of how these patterns can inform future research.
ABHD16A is a phospholipid-modifying endoplasmic reticulum (ER) membrane protein required for both mitochondrial fission and fusion machinery recruitment to ER-associated mitochondrial constrictions.
Kevin P Koster, Walter Francesconi ... Akira Yoshii
NMDA receptor function is regulated by protein depalmitoylation during visual cortical maturation and is dysfunctional in infantile neuronal ceroid lipofuscinosis.
A multi-disciplined approach uncovered microRNA-199a/b-5p as important regulators of chondrogenesis, which negatively regulate mRNAs such as FZD6, ITGA3, and CAV1 for protective purposes during chondrogenesis.
Trygve E Bakken, Cindy TJ van Velthoven ... Bosiljka Tasic
Transcriptomic differences between relay neurons in the mature mammalian dLGN are subtle relative to striking differences in morphology and cortical projection targets.
AhCobQ, a novel bacterial lysine deacetylase, functions independently of NAD+ and Zn2+, revealing a previously unknown domain and broad implications for metabolic regulation in prokaryotic systems.
BisMapR reveals strand-specific R-loops with high resolution at small-scale genomic features including bidirectionally transcribed promoters and enhancers.
TIM23 core deficiency specifically impacts the oxidative phosphorylation and the mitochondrial ribosome complexes and, unexpectedly, leads to reduction of plasma membrane voltage-dependent potassium channels in neurons.
