Opposing gradients of activin A and follistatin within the spiral shaped mammalian cochlea instruct the graded pattern of mechano-sensory hair cell formation.

Flatworm regeneration of lost tissue relies on a mechanism distinct from that used for routine tissue turnover.

The application of long-read sequencing to the pea aphid wing dimorphism system reveals genomic structural divergence as a genetic mechanism of adaptation.

Activin class member, activin C, is a canonical TGFβ family member that signals through the type I receptor, action receptor-like kinase 7 and is resistant to follistatin antagonism.

A gene expression-guided functional screen identifies factors and cell types that regulate diverse aspects of neural regeneration in planarians.

The lens-averted domains of the optic vesicle are reservoirs of neuroretinal cells that flow into the developing optic cup in a process that is critically influenced by BMP signaling.

The dynamic homeostasis of the planarian epidermis serves as an experimental paradigm to study stem cell dynamics and post-mitotic specification of diverse functional cell fates.

The non-signaling complex formed by Activin A and ACVR1 is operant in vivo and is required to temper the degree of heterotopic ossification in the genetic disorder fibrodysplasia ossificans progressiva.