Leon Y Chan, Christopher F Mugler ... Karsten Weis
Non-invasive mRNA stability measurements reveal that transcript lifetime is governed by a competition with translation initiation on a transcriptome-wide level.
Transcriptomes of cells in the Drosophila visual system combined with anatomy and other information reveal new functional insight into the visual circuit.
Esteban Suárez-Delgado, Maru Orozco-Contreras ... Leon D Islas
Combined patch-clamp fluorometry with ANAP, a fluorescent non-canonical amino acid, uncovers transitions in the activation pathway of human HV1 that are modulated by voltage and the pH gradient.
The development and functionalities of invariant natural-killer T cells are dependent upon their cell-intrinsic ACC1-mediated de novo fatty acid synthesis, which greatly affect outcomes of allergic asthma.
Feedforward inhibition generates motion anticipation by selectively decreasing sensitivity to a stimulus as it moves across the latter part of a retinal ganglion cell's receptive field.
Accounting for genetic information improved normative models of hippocampal volume in humans by accounting for change equivalent to around 3 years of normal loss for a person aged 65.
Inositol polyphosphate multikinase physically binds to the core subunits of SWI/SNF complex and plays an important role in regulating BRG1 occupancy and BRG-mediated chromatin accessibility in mouse embryonic stem cells.
Fertilizing mouse spermatozoa, characterized by intact CatSper channels, lack of protein tyrosine phosphorylation, and reacted acrosomes, in the female reproductive tract provide molecular insight into sperm selection for successful fertilization.
Geoffrey W Meissner, Aljoscha Nern ... FlyLight Project Team
Single neuron images of Drosophila driver lines reveal neuron shape and are searchable, enabling comparisons to electron microscopy and prediction of intersectional neuron targeting strategies.