Functional analyses provide evidence for a complex Nod factor signalling where NFRe is necessary for maintaining an optimal symbiotic signalling in the susceptible root zone, and initiation of nodule primordia on the expanding root system.

NOD-like receptor NLRP12 is a critical regulator of hepatocyte proliferation and its activation could be therapeutically used to suppress hepatocellular carcinoma.

Ectopic expression of Symbiosis Receptor-like Kinase (SYMRK) in roots of the legume Lotus japonicus resulted in spontaneous activation of nodule organogenesis and mycorrhiza-related gene expression in the absence of microbial symbionts or signalling molecules.

A model of efficient coding by olfactory neurons explains context-dependence observed in the effect of perturbations to the olfactory environment.

Preclinical multilaboratory studies are a robust method to assess promising interventions.

As a result of frequent gene duplication and haplotypic variation, a family of immune genes in the model vertebrate zebrafish has thousands of gene copies that are population- or individual-specific.

The chitin-triggered immune response is mediated by a LYK5 and CERK1 receptor complex in Arabidopsis.

Activation of TRPV4 induced increases in Ca²⁺ influx, activated CaMKII, enhanced pro-inflammatory NFκB-NLRP3 signaling, and promoted inflammation response, thus contributing to pathological cardiac remodeling.

A genome-wide in vivo CRISPR screen identifies an IL-20/IL20RA-mediated crosstalk between peritoneum mesothelial cells and ovarian cancer cells that promotes the formation of M1-like macrophages to prevent ovarian cancer metastasis.

The new vaccine candidate for tuberculosis displays superior protection against disease when compared the currently available vaccine, and can potentially provide new options for global childhood vaccination programs.