Martina Rangl, Nicolaus Schmandt ... Simon Scheuring
High-speed atomic force microscopy reveals that the open state of the divalent ion channel CorA is highly dynamic and defined by the fast exchange between conformations.
The secreted sugar-binding protein galectin-8 causes osteoblasts to secrete factors that promote the differentiation of bone marrow cells into osteoclasts; targeting this protein could therefore potentially help treat diseases associated with excessive bone loss.
Site-specific modification of NEMO facilitates RANKL signal specificity in myeloid progenitors and serves as a potential target to modulate inflammatory osteolysis through ISG15-dependent autophagy.
1H-Magnetic resonance spectroscopy at 14T reveals a metabolic signature for anti-depressant-like effects of acetyl-L-carnitine in nucleus accumbens of susceptible mouse.
Katherine B LeClair, Kenny L Chan ... Scott J Russo
Socially dominant mice, unlike subordinates, are protected from displaying a common stress-associated behavioral deficit, social avoidance, following exposure to multiple kinds of chronic stress.