102 results found
    1. Computational and Systems Biology
    2. Developmental Biology

    High-throughput mathematical analysis identifies Turing networks for patterning with equally diffusing signals

    Luciano Marcon, Xavier Diego ... Patrick Müller
    Realistic reaction-diffusion signaling networks that include cell-autonomous factors can robustly form self-organizing spatial patterns for any combination of diffusion coefficients without requiring differential diffusivity.
    1. Cell Biology

    Role of competition between polarity sites in establishing a unique front

    Chi-Fang Wu, Jian-Geng Chiou ... Daniel J Lew
    In budding yeast, nascent polarity sites engage in a winner-takes-all contest to determine a single front.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Shearing in flow environment promotes evolution of social behavior in microbial populations

    Gurdip Uppal, Dervis Can Vural
    Shearing in fluid flow induces or enhances budding dispersal in microbial populations, resulting in stronger cooperative behavior.
    1. Computational and Systems Biology
    2. Developmental Biology

    A quantitative modelling approach to zebrafish pigment pattern formation

    Jennifer P Owen, Robert N Kelsh, Christian A Yates
    A mathematical modelling approach to understanding zebrafish stripe pattern formation exemplifies a biological rule-set sufficient to generate wild-type and a diverse range of mutant patterns.
    1. Ecology

    Linking spatial self-organization to community assembly and biodiversity

    Bidesh K Bera, Omer Tzuk ... Ehud Meron
    A trait-based model of dryland vegetation uncovers the roles of spatial self-organization in maintaining biodiversity in a changing climate and offers novel ways of managing ecosystems at risk.
    1. Microbiology and Infectious Disease

    HetL, HetR and PatS form a reaction-diffusion system to control pattern formation in the cyanobacterium nostoc PCC 7120

    Xiaomei Xu, Véronique Risoul ... Amel Latifi
    Genetic, biochemistry and modeling approaches reveal elements of a Turing-type reaction-diffusion system to control pattern formation in differentiating cyanobacterial filaments.
    1. Computational and Systems Biology

    Spatial–temporal order–disorder transition in angiogenic NOTCH signaling controls cell fate specification

    Tae-Yun Kang, Federico Bocci ... Andre Levchenko
    The transition from a restrictive patterning mechanism to one sensitive to a variety of environmental cues in NOTCH-mediated angiogenesis offers crucial insights into vascularization in damaged organs and cancer therapy.
    1. Physics of Living Systems

    Cells use molecular working memory to navigate in changing chemoattractant fields

    Akhilesh Nandan, Abhishek Das ... Aneta Koseska
    Combined experimental and theoretical analysis identifies a molecular mechanism akin to working memory that enables single cells to perform complex navigation tasks in changing growth factor fields, beyond simple stimulus-response associations.
    1. Neuroscience

    Brian 2, an intuitive and efficient neural simulator

    Marcel Stimberg, Romain Brette, Dan FM Goodman
    Brian 2 is a software package for neural simulations that makes it both easy and computationally efficient to define original models for computational experiment.
    1. Developmental Biology
    2. Physics of Living Systems

    Tissue Organization: When cells get in the flow

    Giovanna M Collu, Marek Mlodzik
    New imaging approaches question a long-standing model for how the eyes of fruit flies acquire their geometric patterning.
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