1,866 results found
    1. Neuroscience

    Precision-based causal inference modulates audiovisual temporal recalibration

    Luhe Li, Fangfang Hong ... Michael S Landy
    Audiovisual temporal recalibration relies on the same causal-inference processes that govern cross-modal perception.
    1. Neuroscience

    Contrary neuronal recalibration in different multisensory cortical areas

    Fu Zeng, Adam Zaidel, Aihua Chen
    Single-unit recordings from cortical neurons in behaving macaque monkeys expose differential aspects of multisensory plasticity across different multisensory areas during visual–vestibular recalibration.
    1. Neuroscience

    Integrating prediction errors at two time scales permits rapid recalibration of speech sound categories

    Itsaso Olasagasti, Anne-Lise Giraud
    Keeping flexible adaptable representations of speech categories at different time scales allows the brain to maintain stable perception in the face of varying speech sound characteristics.
    1. Neuroscience

    Shared neural underpinnings of multisensory integration and trial-by-trial perceptual recalibration in humans

    Hame Park, Christoph Kayser
    Facing discrepancies in the sensory environment, multisensory information is combined in the medial superior parietal cortex to guide immediate judgements and to also adjust subsequent unisensory perception.
    1. Computational and Systems Biology

    Calibration and analysis of genome-based models for microbial ecology

    Stilianos Louca, Michael Doebeli
    A novel computation tool for microbial community modeling predicts the evolution and diversification of E. coli in laboratory evolution experiments and gives insight into the underlying metabolic processes.
    1. Cell Biology
    2. Computational and Systems Biology

    Development, calibration, and validation of a novel human ventricular myocyte model in health, disease, and drug block

    Jakub Tomek, Alfonso Bueno-Orovio ... Blanca Rodriguez
    A computer model of human cardiomyocyte was produced and validated on independent datasets, overcoming shortcomings of its predecessors, also yielding broadly relevant insights and results on major ionic currents.
    1. Neuroscience

    Relationship between simultaneously recorded spiking activity and fluorescence signal in GCaMP6 transgenic mice

    Lawrence Huang, Peter Ledochowitsch ... Lu Li
    Simultaneous calcium imaging and cell-attached recording in GCaMP6 transgenic mice in vivo reveals spiking-fluorescence relationship that supports more refined inference of neuronal activities from calcium imaging data.
    1. Evolutionary Biology

    Phylogenomic analyses of echinoid diversification prompt a re-evaluation of their fossil record

    Nicolás Mongiardino Koch, Jeffrey R Thompson ... Greg W Rouse
    Phylogenomics of sea urchins clarifies their origins and diversification history, reveals surprising discrepancies with their rich fossil record, and serves as basis to explore the sensitivity of time calibration analysis.
    1. Biochemistry and Chemical Biology
    2. Immunology and Inflammation

    Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist

    Caleb R Glassman, Leon Su ... K Christopher Garcia
    A panel of interleukin-2 partial agonists designed to exploit distinct immune cell response thresholds enabled selective activation of regulatory T cells in vivo.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Polygenic risk scores for the prediction of common cancers in East Asians: A population-based prospective cohort study

    Peh Joo Ho, Iain BeeHuat Tan ... Jingmei Li
    Site-specific polygenic risk scores can stratify the risk of developing breast, prostate, and colorectal cancers in this East Asian population.

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