Single-unit recordings from cortical neurons in behaving macaque monkeys expose differential aspects of multisensory plasticity across different multisensory areas during visual–vestibular recalibration.
Keeping flexible adaptable representations of speech categories at different time scales allows the brain to maintain stable perception in the face of varying speech sound characteristics.
Facing discrepancies in the sensory environment, multisensory information is combined in the medial superior parietal cortex to guide immediate judgements and to also adjust subsequent unisensory perception.
A novel computation tool for microbial community modeling predicts the evolution and diversification of E. coli in laboratory evolution experiments and gives insight into the underlying metabolic processes.
Jakub Tomek, Alfonso Bueno-Orovio ... Blanca Rodriguez
A computer model of human cardiomyocyte was produced and validated on independent datasets, overcoming shortcomings of its predecessors, also yielding broadly relevant insights and results on major ionic currents.
Simultaneous calcium imaging and cell-attached recording in GCaMP6 transgenic mice in vivo reveals spiking-fluorescence relationship that supports more refined inference of neuronal activities from calcium imaging data.
Nicolás Mongiardino Koch, Jeffrey R Thompson ... Greg W Rouse
Phylogenomics of sea urchins clarifies their origins and diversification history, reveals surprising discrepancies with their rich fossil record, and serves as basis to explore the sensitivity of time calibration analysis.
Caleb R Glassman, Leon Su ... K Christopher Garcia
A panel of interleukin-2 partial agonists designed to exploit distinct immune cell response thresholds enabled selective activation of regulatory T cells in vivo.