The ever-worsening climate and ecological crises calls for life scientists to engage in advocacy and activism to galvanise governments and the public into action.

A fluoroquinolone resistant variant of Salmonella Typhi has emerged that is likely to be widespread in the Indian subcontinent; therefore fluoroquinolones should not be recommended for empirical typhoid fever therapy in this setting.

Ending the TB epidemic requires scaling up access to new TB tools so that they can benefit the patients in low- and middle-income countries that need them the most.

Precise control of microtubule architecture greatly increases the force that the spindle can exert on chromosomes.

A EASAC working group on gain-of-function research has emphasised the importance of ensuring that the necessary safeguards and policies are in place.

Adding a One Health approach to a research framework for minority health and health disparities encourages the exploration of new avenues of inquiry, multidisciplinary collaboration, and the consideration of new determinants of health.

Activation of lung macrophage nitric oxide synthase-3 improves both bacterial clearance and outcome in primary and secondary pneumonia models.

Universities must change so that the scientific enterprise can respond to the climate crisis.

20 emerging issues in bioengineering that will have profound impacts on society have been identified.

This nationwide register-based study of diabetes risk after colectomy suggests that the left colon contributes to maintenance of glucose homeostasis.