Relative hydraulic resistance, shear rate, and pressure in a vascular network integrate the network's architecture via fluid flow, and determine vein dynamics, with a time delay, in the prototypical organism Physarum polycephalum.

Unprecedented 4D spatiotemporal infant regional cerebral blood flow framework and region-specific physiology–function coupling across infancy were elucidated, highlighting strong physiology–function coupling specifically at the default-mode network to meet extraneuronal metabolic demand for network emergence.

The number of inflows and outflows at the occluded capillary governs the local flow reduction, and the different topological configurations are probably designed for distinct functional tasks.

Compressing the actomyosin network by cortical flow causes filaments to align and form a constricting ring.

In developing neural cell cultures, information flows lock-in early and nodes undertake specialised computational roles.

A practical toolbox for application of Granger causality inference to calcium imaging data identifies strong driver neurons in the locus of the mesencephalic locomoter region in larval zebrafish.

A threshold level of blood flow initiates developmental blood vessel regression; this threshold can be regulated by non-canonical Wnt ligands.

Behavioural states emerge from variability in the complexity of underlying active contraction dynamics in a single-cell, network-shaped forager.

A synaptic F-actin network tightly controls the flow of synaptic vesicles during exocytosis at the inner hair cell ribbons.

Galectin-9-deficient mice develop spontaneous autoimmunity, driven by a decreased threshold of B cell activation and enhanced auto-antigen delivery to the spleen by increased B1a-derived autoantibodies.