Imaging mass cytometry simultaneously lights up distinct immune cells in the brain.

ImmunoCluster permits nonspecialist users to interrogate liquid and imaging mass, and flow cytometry datasets, resolving novel layers of cellular heterogeneity and insight, as well as producing publishable outputs and figures.

Cannabinoid receptors CNR1 and CNR2 play distinct roles in endometriosis pathogenesis, potentially contributing to disease initiation and progression through differential modulation of T cell function and the lesion microenvironment.

A neutrophil-CAF-tumor cell IL-1β/IL-6/STAT-3 signaling axis in the pancreatic tumor microenvironment underlies the association between neutrophil-to-lymphocyte ratio dynamics and pathologic response in patients with pancreatic ductal adenocarcinoma undergoing neoadjuvant therapy.

Penetration of the fluoroquinolones in tuberculosis lesions is heterogeneous even in fully cellular areas, is driven by macrophage content and decreases as the distance from lesion outer rim increases.

Circulating immune cells reflect intra-tumoural immunity and can predict response to systemic therapy in head and neck cancer.

A new gene expression tool enables precise control of protein dosage over a large range and paves the way for new genetic discoveries.

Killer T cells swarm around tumour targets by accelerating the recruitment of distant T cells, which upon arrival and target engagement augment the chemotactic signal in a positive feedback loop.

Rare, virus-specific immune cells in human blood are automatically identified by machine learning algorithm T-REX and characterized for signature features needed for tracking and isolation.

A new automated and unsupervised algorithm, Risk Assessment Population IDentification, identifies risk-stratifying cells in single cell datasets with robust statistical and biological validation.