Arabidopsis RNA processing factor SERRATE associates with the chromatin of intronless genes, which are usually expressed at low levels, to enhance polymerase II association.
Genome-wide profiling of R-loops at near single-nucleotide resolution reveals distinct R-loop boundaries depending on the presence and location of the first exon-intron junction.
Subhendu Roy Choudhury, Anand K Singh ... Saverio Brogna
Deposition of the exon junction complex is thought to be the missing link between pre-mRNA splicing and translation in multicellular organisms, but no evidence of such deposition has been found in Drosophila.
Leonardo Gastón Guilgur, Pedro Prudêncio ... Rui Gonçalo Martinho
The need for efficient pre-RNA splicing during early embryonic development of Drosophila indicates that the constraints imposed by the cell cycle are a force capable of driving changes in Eukaryotic gene architecture.
Madara Ratnadiwakara, Stuart K Archer ... Minna-Liisa Anko
RNA-binding protein SRSF3 mediates critical changes in RNA processing of pluripotency genes, which reveals functional consequences of regulated RNA processing during stem cell self-renewal and early development.
Rtf2 is shown to associate with multiple splicing factors and influence splicing of a subset of introns explaining why previous work erroneously assigned it as a replication restart factor in fission yeast.
Chicken ANP32A, and not chicken ANP32B, supports influenza polymerase activity and thus editing of this single gene may generate chickens that are resilient to influenza virus infection.