44 results found
    1. Chromosomes and Gene Expression
    2. Plant Biology

    Arabidopsis RNA processing factor SERRATE regulates the transcription of intronless genes

    Corinna Speth, Emese Xochitl Szabo ... Sascha Laubinger
    Arabidopsis RNA processing factor SERRATE associates with the chromatin of intronless genes, which are usually expressed at low levels, to enhance polymerase II association.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Genome streamlining in a minute herbivore that manipulates its host plant

    Robert Greenhalgh, Wannes Dermauw ... Merijn R Kant
    The genome of a tiny tomato pest reveals mechanisms that underlie metazoan genome reduction.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Defining the location of promoter-associated R-loops at near-nucleotide resolution using bisDRIP-seq

    Jason G Dumelie, Samie R Jaffrey
    Genome-wide profiling of R-loops at near single-nucleotide resolution reveals distinct R-loop boundaries depending on the presence and location of the first exon-intron junction.
    1. Chromosomes and Gene Expression

    Exon junction complex proteins bind nascent transcripts independently of pre-mRNA splicing in Drosophila melanogaster

    Subhendu Roy Choudhury, Anand K Singh ... Saverio Brogna
    Deposition of the exon junction complex is thought to be the missing link between pre-mRNA splicing and translation in multicellular organisms, but no evidence of such deposition has been found in Drosophila.
    1. Genetics and Genomics

    Normal mitochondrial function in Saccharomyces cerevisiae has become dependent on inefficient splicing

    Marina Rudan, Peter Bou Dib ... Anita Kriško
    Removal of mitochondrial introns (Saccharomyces cerevisiae) from their host genes leads to detrimental increase in their transcript levels.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Requirement for highly efficient pre-mRNA splicing during Drosophila early embryonic development

    Leonardo Gastón Guilgur, Pedro Prudêncio ... Rui Gonçalo Martinho
    The need for efficient pre-RNA splicing during early embryonic development of Drosophila indicates that the constraints imposed by the cell cycle are a force capable of driving changes in Eukaryotic gene architecture.
    1. Chromosomes and Gene Expression

    The RNA helicase UPF1 associates with mRNAs co-transcriptionally and is required for the release of mRNAs from gene loci

    Anand K Singh, Subhendu Roy Choudhury ... Saverio Brogna
    UPF1 associates with nascent transcripts and plays a broad role in nuclear processes of gene expression.
    1. Chromosomes and Gene Expression
    2. Stem Cells and Regenerative Medicine

    SRSF3 promotes pluripotency through Nanog mRNA export and coordination of the pluripotency gene expression program

    Madara Ratnadiwakara, Stuart K Archer ... Minna-Liisa Anko
    RNA-binding protein SRSF3 mediates critical changes in RNA processing of pluripotency genes, which reveals functional consequences of regulated RNA processing during stem cell self-renewal and early development.
    1. Cell Biology

    Schizosaccharomyces pombe Rtf2 is important for replication fork barrier activity of RTS1 via splicing of Rtf1

    Alice M Budden, Murat Eravci ... Antony M Carr
    Rtf2 is shown to associate with multiple splicing factors and influence splicing of a subset of introns explaining why previous work erroneously assigned it as a replication restart factor in fission yeast.
    1. Microbiology and Infectious Disease

    Species specific differences in use of ANP32 proteins by influenza A virus

    Jason S Long, Alewo Idoko-Akoh ... Wendy Barclay
    Chicken ANP32A, and not chicken ANP32B, supports influenza polymerase activity and thus editing of this single gene may generate chickens that are resilient to influenza virus infection.

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