CausalXtract is a computational tool to discover causal effects, beyond classical Granger and Schreiber causality approaches, from live-cell imaging data for a range of fundamental and translational research applications.

ADeS, a novel deep learning approach for apoptosis detection, achieves 98% accuracy in vitro and in vivo while providing unprecedented insights into the spatial–temporal foundation of cell death.

Histone variant H2A.Z is deposited near transcription start sites by the chromatin remodeler SWR1 and seems to be removed by RNA polymerase II at an early stage of transcription elongation.

Type II nuclear receptors do not always compete for a limiting pool of their obligate partner RXRa.

Proximity-assisted photoactivation (PAPA) provides a new way to detect protein–protein interactions in single-molecule imaging of live cells.

A novel, inexpensive, easy-to-use method to analyse traffic along the endosomal pathway in mammalian cells shows that there is coordination between Rab conversion and acidification, but almost none between Rab conversion and recycling.

Sox2 transcription is not correlated with spatial proximity of its essential regulatory enhancer in embryonic stem cells, suggesting gene transcription is not limited to periods of direct enhancer-promoter contact.

Live cell imaging and the in vivo dissection into distinct stages, called landmarks, represents a new methodology for analyzing meiosis in Arabidopsis and likely in other species as well.

A long-term multi-organ co-culture system coupled with quantitative imaging to visualize blood cell cycle progression, analyze polarized blood cell mitosis, and track blood cell differentiation kinetics during Drosophila hematopoiesis in homeostatic condition and following infection.

Lineage tracing at single-cell resolution reveals the presence of mesoteloblasts, the embryonic origin of mesodermal growth zone cells, and diverse cell cycling patterns of these lineages in the 'Polychaete' annelid Platynereis.