Mir155 showed a catabolic effect on osteogenesis and bone mass phenotype via interaction with the S1pr1 gene, suggesting inhibition of Mir155 as a potential approach to bone regeneration and bone defect healing.
Targeting mir128-3p could prevent cardiac insulin resistance in the non-infarcted myocardium and limit cardiac injury after myocardial infarction, delaying the development of heart failure.
Federico A Vignale, Andrea Hernandez Garcia ... Adrian G Turjanski
DNA sequencing of the yerba mate (Ilex paraguariensis) genome reveals convergent genomic changes, biochemical pathways, mutations, and substrate-binding orientations responsible for caffeine biosynthesis when compared to coffee and tea plants.
Retrotransposon-derived messenger RNA plays a critical role in rice root development via sequestration of miR171, which suggests a novel trans-acting regulation by transposable elements.
Eleonora Franzoni, Sam A Booker ... F Gregory Wulczyn
The regulation of Phf6 by miR-128 is a developmental timing mechanism that influences cortical lamination, neuronal morphology and intrinsic excitability.