3 results found
    1. Developmental Biology

    Drosophila neprilysins control insulin signaling and food intake via cleavage of regulatory peptides

    Benjamin Hallier et al.
    The catalytic activity of a Drosophila neprilysin is critical to proper insulin expression and food intake by regulating homeostasis of distinct signaling peptides.
    1. Neuroscience

    Single cell transcriptome atlas of the Drosophila larval brain

    Clarisse Brunet Avalos et al.
    Single-cell transcriptomics identifies cellular composition of the first instar Drosophila brain and the response to starvation.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Somatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers

    Hansen Wang et al.
    The cyclic neuropeptide somatostatin binds to human Aβ1-42 through an interface that critically relies on a specific tryptophan, thereby blocking the propensity of Aβ to aggregate, a critical step in the pathobiology of Alzheimer's disease.

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