A new pipeline of electron microscopy techniques reduces the time required to visualize genetically targeted neurons and their connections by two orders of magnitude.

Using different sets of input sequences to evolutionary reconstruction algorithms results in the exploration of many possible models, the intergration over which produces significantly more accurate models.

The visual message conveyed by retinal neurons to the brain when signaling natural scenes resembles the individual receptive fields only when viewed in context of the neuronal population.

While electron microscopic helical reconstruction is a powerful technique in structural biology, mistakes can be made in determining the helical symmetry, leading to structures that are artifactual.

The body plan of the 407-million-year-old plant fossil Asteroxylon mackiei comprised three developmentally distinct systems of axes.

MotionTracking is freely available software that can generate multi-scale geometrical models of mammalian tissue and perform quantitative analysis of tissue architecture.

A new approach for fast, sparse neural circuit mapping allows circuit structure, physiology, and behavior to be quantified in the same animal and across many animals.

The first comprehensive reconstruction of the evolutionary history of freshwater animals, on example of family Nemacheilidae, across Eurasia with the identification of the main tectonic, geological, and climatic factors influencing it has been described.

Ancestral reconstruction of a signaling pathway reveals the mutations responsible for producing specificity of the two paralogous pathways produced by a duplication event.

Water molecules and amino-acid side chain rotamers have been resolved in the cryoEM structure of T20S proteasome at 2.8 angstroms.