12,623 results found
    1. Chromosomes and Gene Expression
    2. Neuroscience

    The LIM protein complex establishes a retinal circuitry of visual adaptation by regulating Pax6 α-enhancer activity

    Yeha Kim, Soyeon Lim ... Jin Woo Kim
    Regulation of Pax6 expression through the α-enhancer fine-tunes amacrine cell subtype number, and consequently, the visual output of the retina.
    1. Cell Biology

    Formation of a giant unilocular vacuole via macropinocytosis-like process confers anoikis resistance

    Jeongsik Kim, Dahyun Kim ... Dae-Sik Lim
    Formation of a giant unilocular vacuole through a macropinocytosis-like process in cells with disrupted actin cytoskeleton promotes resistance to anoikis.
    1. Epidemiology and Global Health

    How should COVID-19 vaccines be distributed between the Global North and South: a discrete choice experiment in six European countries

    Janina I Steinert, Henrike Sternberg ... Tim Büthe
    In a large discrete choice experiment, respondents from six European countries reveal preferences for global vaccine solidarity, where female, younger, more educated respondents are most likely to prioritise candidates from the Global South in their allocation choices for COVID-19 vaccines.
    1. Biochemistry and Chemical Biology

    Enterococcus faecium secreted antigen A generates muropeptides to enhance host immunity and limit bacterial pathogenesis

    Byungchul Kim, Yen-Chih Wang ... Howard C Hang
    Enterococci faecium encodes unique peptidoglycan composition and remodeling activity that activates host immunity.
    1. Developmental Biology

    Stella modulates transcriptional and endogenous retrovirus programs during maternal-to-zygotic transition

    Yun Huang, Jong Kyoung Kim ... M Azim Surani
    Soon after fertilisation, a critical portion of the embryonic genome is switched on through the actions of maternally inherited Stella, in part through controlling the activation of transposable elements.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    A combination of transcription factors mediates inducible interchromosomal contacts

    Seungsoo Kim, Maitreya J Dunham, Jay Shendure
    A pooled mutational scanning approach for 3D chromosome conformation reveals how multiple transcription factors can jointly specify condition-specific genome conformations.
    1. Cancer Biology

    STRIPAK directs PP2A activity toward MAP4K4 to promote oncogenic transformation of human cells

    Jong Wook Kim, Christian Berrios ... William C Hahn
    ST recruitment of STRIPAK facilitates PP2A-mediated dephosphorylation of MAP4K4 and induces cell transformation highlighting that STRIPAK complex plays a key role in defining PP2A specificity and activity.
    1. Ecology
    2. Genetics and Genomics

    Anopheles homing suppression drive candidates exhibit unexpected performance differences in simulations with spatial structure

    Samuel E Champer, Isabel K Kim ... Jackson Champer
    Continuous space models indicate that current homing suppression drives may have difficulty eliminating wild mosquito populations, but building a successful drive may still be possible with current tools.
    1. Medicine

    Enhancing bone regeneration and osseointegration using rhPTH(1-34) and dimeric R25CPTH(1-34) in an osteoporotic beagle model

    Jeong-Oh Shin, Jong-Bin Lee ... Jin-Woo Kim
    rhPTH(1-34) and dimeric R25CPTH(1-34) significantly promoted bone regeneration and titanium implant osseointegration in an osteoporotic beagle model.
    1. Neuroscience

    ‘Fearful-place’ coding in the amygdala-hippocampal network

    Mi-Seon Kong, Eun Joo Kim ... Jeansok J Kim
    By recording simultaneous spike trains from fear-responsive basal amygdala (BA) and place-responsive dorsal hippocampus (dHPC) neurons in rats foraging for food in a risky predatory situation, a novel BA-dHPC circuit coding mechanism for interfacing danger and place information was revealed.

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