4,988 results found
    1. Computational and Systems Biology
    2. Medicine

    Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats

    Hong Yang, Cheng Zhang ... Adil Mardinoglu
    Inhibiting c-Jun N-terminal kinase exerts a cross-tissue therapeutic effect on metabolic dysfunction induced by sucrose overconsumption in rats.
    1. Ecology

    The larva and adult of Helicoverpa armigera use differential gustatory receptors to sense sucrose

    Shuai-Shuai Zhang, Pei-Chao Wang ... Chen-Zhu Wang
    The sweet taste receptors in the cotton bollworm (Helicoverpa armigera) are evolved to adapt towards the larval and adult foods with different types and amounts of sugar.
    1. Neuroscience

    Chemogenetic inhibition of the medial prefrontal cortex reverses the effects of REM sleep loss on sucrose consumption

    Kristopher McEown, Yohko Takata ... Michael Lazarus
    Loss of REM sleep increases sucrose and fat consumption in mice; and inhibiting the prefrontal cortex reverses the increased consumption of sucrose, but not fat, following REM sleep loss.
    1. Neuroscience

    Sucrose intensity coding and decision-making in rat gustatory cortices

    Esmeralda Fonseca, Victor de Lafuente ... Ranier Gutierrez
    The neural representation of perceived sucrose intensity was contained in the firing rate and spike-timing of a 'small' population of neurons distributed across the Insula and Orbitofrontal taste cortices.
    1. Chromosomes and Gene Expression
    2. Neuroscience

    A receptor and neuron that activate a circuit limiting sucrose consumption

    Ryan M Joseph, Jennifer S Sun ... John R Carlson
    Although sugar-sensing taste neurons typically promote feeding, a taste neuron in the Drosophila pharynx limits feeding via the IR60b receptor; thus, revealing a new element in the circuit logic of feeding control.
    1. Neuroscience

    Hypothalamic melanin concentrating hormone neurons communicate the nutrient value of sugar

    Ana I Domingos, Aylesse Sordillo ... Jeffrey M Friedman
    Natural sugars are preferred over artificial sweeteners because of their nutritional content, which is sensed by MCH neurons in the lateral hypothalamus.
    1. Cell Biology

    Isoform-specific mutation in Dystonin-b gene causes late-onset protein aggregate myopathy and cardiomyopathy

    Nozomu Yoshioka, Masayuki Kurose ... Hirohide Takebayashi
    Dystonin-b-specific mutant mice exhibit late-onset myopathy and cardiomyopathy.
    1. Evolutionary Biology
    2. Stem Cells and Regenerative Medicine

    A conserved strategy for inducing appendage regeneration in moon jellyfish, Drosophila, and mice

    Michael J Abrams, Fayth Hui Tan ... Lea Goentoro
    Amino acid and sugar supplement induce appendage/limb regeneration in cnidarians, insects, and mammals.
    1. Neuroscience

    Coherent theta activity in the medial and orbital frontal cortices encodes reward value

    Linda M Amarante, Mark Laubach
    The more you want it or the better it is, the stronger is medial frontal theta (paraphrased from a retweet of the preprint by Dr James Hyman).
    1. Evolutionary Biology

    Improved use of a public good selects for the evolution of undifferentiated multicellularity

    John H Koschwanez, Kevin R Foster, Andrew W Murray
    The ability to share resources for the benefit of all members of a group may have driven ancient organisms to evolve from a unicellular to a multicellular state.

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