1,561 results found
    1. Stem Cells and Regenerative Medicine

    Activating the regenerative potential of Müller glia cells in a regeneration-deficient retina

    Katharina Lust, Joachim Wittbrodt
    Müller glia cells in the medaka (Oryzias latipes) retina act as lineage restricted progenitors which only regenerate photoreceptors but can be activated to perform as potent stem cells using Sox2.
    1. Ecology
    2. Plant Biology

    Present-day central African forest is a legacy of the 19th century human history

    Julie Morin-Rivat, Adeline Fayolle ... Jean-Louis Doucet
    The cessation of major anthropogenic disturbances since European colonization in the forests of central Africa leads to a canopy closing, and to the disappearance of certain light-demanding tree species.
    1. Neuroscience

    Modeling apical and basal tree contribution to orientation selectivity in a mouse primary visual cortex layer 2/3 pyramidal cell

    Konstantinos-Evangelos Petousakis, Jiyoung Park ... Panayiota Poirazi
    Apical and basal dendrites contribute differently to single-neuron orientation selectivity, highlighting the impact of feedforward and feedback signal interactions.
    1. Neuroscience

    An expanding manifold in transmodal regions characterizes adolescent reconfiguration of structural connectome organization

    Bo-yong Park, Richard AI Bethlehem ... Boris C Bernhardt
    Manifold learning of longitudinal brain network data provides novel insights into adolescent structural connectome maturation, and how multiple scales of cortical and subcortical organization interact in typical neurodevelopment.
    1. Physics of Living Systems
    2. Stem Cells and Regenerative Medicine

    DUCT reveals architectural mechanisms contributing to bile duct recovery in a mouse model for Alagille syndrome

    Simona Hankeova, Jakub Salplachta ... Emma Rachel Andersson
    Dual resin casting of multiple lumenized systems followed by microCT allows visualization, digitalization, and quantification of architectural parameters defining the vascular and biliary systems in liver revealing new phenotypes.
    1. Evolutionary Biology

    Coevolution of the CDCA7-HELLS ICF-related nucleosome remodeling complex and DNA methyltransferases

    Hironori Funabiki, Isabel E Wassing ... Thomas Carroll
    Coevolution analysis suggests that a DNA methylation-related role for the nucleosome remodeling ATPase HELLS and its activator CDCA7 was broadly inherited from the last eukaryotic common ancestor.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Hfq CLASH uncovers sRNA-target interaction networks linked to nutrient availability adaptation

    Ira Alexandra Iosub, Robert Willem van Nues ... Sander Granneman
    High-throughput RNA-RNA interaction analysis uncovers many novel sRNA-target interactions at various growth stages in Escherichia coli.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Eya2 promotes cell cycle progression by regulating DNA damage response during vertebrate limb regeneration

    Konstantinos Sousounis, Donald M Bryant ... Jessica L Whited
    Experimental manipulation of a core DNA damage response factor and cell-cycle checkpoint regulators reveals a key role for these processes in the progenitor cells that fuel limb regeneration.
    1. Ecology

    Linking spatial patterns of terrestrial herbivore community structure to trophic interactions

    Jakub Witold Bubnicki, Marcin Churski ... Dries PJ Kuijper
    The spatial interactions between humans, large carnivores and herbivores cascade down in a complex but predictable way to lower trophic levels affecting regeneration of tree species in a temperate forest.
    1. Cell Biology
    2. Computational and Systems Biology

    Patterns of interdivision time correlations reveal hidden cell cycle factors

    Fern A Hughes, Alexis R Barr, Philipp Thomas
    Bayesian inference identifies hidden dynamics underlying noisy cell division data.

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